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Collaboration and license agreements - Summarizes the deferred revenue amounts allocated to performance obligations (Details) - USD ($) $ in Thousands | Jun. 30, 2026 | Dec. 31, 2025
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Total Roche Agreement deferred revenue | $ 105,623 | $ 111,332
Roche Agreement [Member] |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Total Roche Agreement deferred revenue | 15,179 | 22,657
Roche Agreement [Member] | Research and Development of Intial Targets [Member] |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Total Roche Agreement deferred revenue | 7,180 | 14,140
Roche Agreement [Member] | Research and Development for Replacement Targets [Member] |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Total Roche Agreement deferred revenue | $ 7,999 | $ 8,517

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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 808 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (d) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479402/808-10-50-1 + Details
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- Definition Amount of deferred income and obligation to transfer product and service to customer for which consideration has been received or is receivable. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(26)(c)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 + Details
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Period Type: | instant

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- Details
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- Details
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- Details
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