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v3.25.3

Segment reporting - Segment Expenses (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 | Sep. 30, 2024 | Sep. 30, 2025 | Sep. 30, 2024
Segment Reporting Information |  |  |  |
Research and development expense | $ 19,249 | $ 17,985 | $ 56,071 | $ 45,482
Stock-based compensation | 4,396 | 5,508 | 14,093 | 14,401
Depreciation and amortization | 2,842 | 3,355 | 8,914 | 10,155
Total operating expenses | 30,532 | 30,596 | 91,426 | 82,983
Segment One |  |  |  |
Segment Reporting Information |  |  |  |
Personnel | 10,488 | 9,813 | 30,638 | 29,137
Stock-based compensation | 4,396 | 5,508 | 14,093 | 14,401
General & administrative | 3,531 | 3,799 | 11,158 | 11,352
Depreciation and amortization | 2,842 | 3,355 | 8,914 | 10,155
Total operating expenses | 30,532 | 30,596 | 91,426 | 82,983
Asset Impairment Charges | 0 | 1,125 | 0 | 1,125
Drug creation program and platform | Segment One |  |  |  |
Segment Reporting Information |  |  |  |
Research and development expense | 5,669 | 4,144 | 14,963 | 11,635
External preclinical and clinical development | Segment One |  |  |  |
Segment Reporting Information |  |  |  |
Research and development expense | $ 3,606 | $ 2,852 | $ 11,660 | $ 5,178

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