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Stock-based compensation (Tables)

9 Months Ended

Sep. 30, 2025

Share-Based Payment Arrangement [Abstract]

Schedule of Allocation of Share-based Compensation

Total stock-based compensation expense related to all of the Company’s stock-based awards was recorded in the condensed consolidated statements of operations and comprehensive loss as follows (in thousands):

						For the Three Months Ended September 30,												For the Nine Months Ended September 30,
						2025						2024						2025						2024
Research and development						1,982						2,010						$	6,020					$	5,577
Selling, general and administrative						2,414						3,498						8,073						8,824
Total stock-based compensation expense						$	4,396					$	5,508					$	14,093					$	14,401

Schedule of Stock Option Activity

Activity for stock options is shown below:

			Number of Options						Weighted Average Exercise Price per Share						Weighted Average Remaining Contractual Term (in years)						Aggregate Intrinsic Value (in thousands $)
Outstanding at December 31, 2024			19,177,571						$	3.39					7.6						$	7,317
Granted			6,512,400						3.16
Exercised			(864,563)						2.26												1,738
Canceled/Forfeited			(2,293,910)						3.05
Expired			(626,082)						7.33
Outstanding at September 30, 2025			21,905,416						3.29						7.7						$	9,804
Exercisable at September 30, 2025			10,105,606						$	3.41					6.6						$	6,621

Schedule of Determination of Fair Value

The estimated grant-date fair value of all the Company’s stock options was calculated using the Black-Scholes option pricing model, based on the following assumptions:

						For the Three Months Ended September 30,												For the Nine Months Ended September 30,
						2025						2024						2025						2024
Expected term (in years)						5.8-6.1						6.0-6.1						5.5-6.1						5.5-6.1
Volatility						91%-91%						82%-84%						90%-92%						81%-84%
Risk-free interest rate						3.8%-4.0%						3.7%-4.4%						3.8%-4.4%						3.7%-4.6%
Dividend Yield						—%						—%						—%						—%

Schedule of Non-vested Share Activity

Activity for restricted stock units is shown below:

			Number of Shares						Weighted Average Grant Date Fair Value
Unvested as of December 31, 2024			3,711,710						$	3.12
Granted			1,667,362						3.19
Vested			(469,008)						3.93
Forfeitures			(489,704)						2.56
Unvested as of September 30, 2025			4,420,360						$	3.12

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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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Tabular disclosure of the changes in outstanding nonvested shares.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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