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Net loss per share - Anti-dilutive Securities (Details) - shares
9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Antidilutive Securities Excluded from Computation of Earnings Per Share    
Antidilutive securities excluded from computation of earnings per share, amount (in shares) 26,325,776 24,012,997
Stock options    
Antidilutive Securities Excluded from Computation of Earnings Per Share    
Antidilutive securities excluded from computation of earnings per share, amount (in shares) 21,905,416 19,565,154
Restricted stock units    
Antidilutive Securities Excluded from Computation of Earnings Per Share    
Antidilutive securities excluded from computation of earnings per share, amount (in shares) 4,420,360 4,348,657
Unvested restricted stock    
Antidilutive Securities Excluded from Computation of Earnings Per Share    
Antidilutive securities excluded from computation of earnings per share, amount (in shares) 0 99,186