<SEC-DOCUMENT>0001104659-22-047608.txt : 20220420
<SEC-HEADER>0001104659-22-047608.hdr.sgml : 20220420
<ACCEPTANCE-DATETIME>20220420101030
ACCESSION NUMBER:		0001104659-22-047608
CONFORMED SUBMISSION TYPE:	DEFA14A
PUBLIC DOCUMENT COUNT:		3
FILED AS OF DATE:		20220420
DATE AS OF CHANGE:		20220420

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TEKLA LIFE SCIENCES INVESTORS
		CENTRAL INDEX KEY:			0000884121
		IRS NUMBER:				043147016
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		DEFA14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	811-06565
		FILM NUMBER:		22836642

	BUSINESS ADDRESS:	
		STREET 1:		100 FEDERAL STREET
		STREET 2:		19TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
		BUSINESS PHONE:		6177728515

	MAIL ADDRESS:	
		STREET 1:		100 FEDERAL STREET
		STREET 2:		19TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	H&Q LIFE SCIENCES INVESTORS
		DATE OF NAME CHANGE:	19920929
</SEC-HEADER>
<DOCUMENT>
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<p style="font: 14pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><font style="font-family: Times New Roman, Times, Serif"><b>UNITED
STATES<br>
</b></font><b>SECURITIES AND EXCHANGE COMMISSION</b></p>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><b>Washington, D.C. 20549</b></p>

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<p style="font: 14pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><b>SCHEDULE 14A</b></p>

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<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><b>Proxy Statement Pursuant to Section 14(a) of<br>
the Securities Exchange Act of 1934 (Amendment No. &#xa0;&#xa0;&#xa0;&#xa0;)</b></p>

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    <td colspan="2" style="padding-right: 0.7pt; padding-left: 0.7pt"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Check the appropriate box:</font></td></tr>
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    <td style="padding-right: 0.7pt; padding-left: 0.7pt"><font style=" font-size: 10pt"><font style="font-family: Wingdings">&#168;</font></font></td>
    <td style="padding-right: 0.7pt; padding-left: 0.7pt"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Preliminary Proxy Statement</font></td></tr>
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    <td style="padding-right: 0.7pt; padding-left: 0.7pt"><font style="font-family: Wingdings">&#168;</font></td>
    <td style="padding-right: 0.7pt; padding-left: 0.7pt"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt"><b>Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))</b></font></td></tr>
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    <td style="padding-right: 0.7pt; padding-left: 0.7pt"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Definitive Proxy Statement</font></td></tr>
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    <td style="padding-right: 0.7pt; padding-left: 0.7pt"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Definitive Additional Materials</font></td></tr>
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    <td style="padding-right: 0.7pt; padding-left: 0.7pt"><font style=" font-size: 10pt"><font style="font-family: Wingdings">&#168;</font></font></td>
    <td style="padding-right: 0.7pt; padding-left: 0.7pt"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Soliciting Material under &#xa7;240.14a-12</font></td></tr>
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    <td colspan="2" style="padding-right: 0.7pt; padding-left: 0.7pt; text-align: center">&#xa0;</td></tr>
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    <td colspan="2" style="border-bottom: Black 1pt solid; padding-right: 0.7pt; padding-left: 0.7pt; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 14pt"><b>Tekla Life Sciences Investors</b></font></td></tr>
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    <td colspan="2" style="padding-right: 0.7pt; padding-left: 0.7pt; text-align: center"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Name of Registrant as Specified In Its Charter)</font></td></tr>
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    <td colspan="2" style="padding-right: 0.7pt; padding-left: 0.7pt"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Payment of Filing Fee (Check the appropriate box):</font></td></tr>
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    <td style="padding-right: 0.7pt; padding-left: 0.7pt"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">No fee required.</font></td></tr>
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    <td style="padding-right: 0.7pt; padding-left: 0.7pt"><font style="font-family: Times New Roman, Times, Serif; font-size: 10pt">Fee paid previously with preliminary materials.</font></td></tr>
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    <td style="padding-right: 0.7pt; padding-left: 0.7pt">Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a6(i)(1) and 0-11</td></tr>
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<P STYLE="margin: 0pt">&nbsp;</P>

<P STYLE="margin: 0pt"></P>

<P STYLE="font: 17pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B><U>BEFORE YOU VOTE &ndash; </U></B></P>

<P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 17pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B><U>IMPORTANT INFORMATION REGARDING THE ENCLOSED
BALLOT!</U></B></P>

<P STYLE="font: 17pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 17pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 16pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>To vote your shares </B></P>

<P STYLE="vertical-align: baseline; font: 14pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-size: 18pt; color: red"><B><I><U>ALONG</U></I></B></FONT><B><I><U>
<FONT STYLE="font-size: 16pt; text-transform: uppercase">WITH the recommendations of the Board of Trustees</FONT></U></I></B></P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B><I><U><FONT STYLE="font-size: 16pt; text-transform: uppercase"></FONT></U></I></B><B> <FONT STYLE="font-size: 16pt">of
Tekla Life Sciences Investors (&ldquo;HQL&rdquo;) </FONT></B></P>

<P STYLE="font: 12pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 16pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>your ballot must look like this:</B></P>

<P STYLE="font: 16pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 16pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 12pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 11pt Arial, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left; width: 3%">&nbsp;</TD>
    <TD><FONT STYLE="font-size: 16pt"><B><U>PROPOSALS</U></B></FONT></TD>
    <TD STYLE="width: 15%; text-align: center"><FONT STYLE="font-size: 14pt"><B>FOR ALL</B></FONT></TD>
    <TD STYLE="width: 15%; text-align: center"><FONT STYLE="font-size: 14pt"><B>WITHHOLD<BR>
 ALL</B></FONT></TD>
    <TD STYLE="width: 15%; text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 7pt; text-align: left"><FONT STYLE="font-size: 12pt">1.</FONT></TD>
    <TD STYLE="padding-bottom: 7pt">
    <P STYLE="font: 12pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">Election of Trustees &ndash; 1.1 &ndash; Rakesh K. Jain, Ph.D.</P>
    <P STYLE="font: 12pt Arial, Helvetica, Sans-Serif; margin-left: 1.66in; text-align: left; margin-top: 0pt; margin-bottom: 0pt">1.2 &ndash; Thomas M. Kent, CPA</P>
    <P STYLE="font: 12pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B><IMG SRC="tm2213036d1_defa14aimg001.jpg" ALT=""></B></FONT></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B><IMG SRC="tm2213036d1_defa14aimg002.jpg" ALT=""></B></FONT></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 7pt; text-align: left">&nbsp;</TD>
    <TD STYLE="padding-bottom: 7pt">&nbsp;</TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center">&nbsp;</TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center">&nbsp;</TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left"><FONT STYLE="font-size: 14pt"><B>&nbsp;</B></FONT></TD>
    <TD><FONT STYLE="font-size: 14pt"><B>&nbsp;</B></FONT></TD>
    <TD STYLE="vertical-align: middle; text-align: center"><FONT STYLE="font-size: 14pt"><B>FOR</B></FONT></TD>
    <TD STYLE="vertical-align: middle; text-align: center"><FONT STYLE="font-size: 14pt"><B>AGAINST</B></FONT></TD>
    <TD STYLE="vertical-align: middle; text-align: center"><FONT STYLE="font-size: 14pt"><B>ABSTAIN</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 7pt; text-align: left">&nbsp;</TD>
    <TD STYLE="padding-bottom: 7pt">&nbsp;</TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center">&nbsp;</TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center">&nbsp;</TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 7pt; text-align: left"><FONT STYLE="font-size: 12pt">2.</FONT></TD>
    <TD STYLE="padding-bottom: 7pt"><FONT STYLE="font-size: 12pt">The ratification or rejection of the selection of Deloitte &amp; Touche LLP as the independent registered public accountants of the Fund for the fiscal year ending September 30, 2022;</FONT></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"><IMG SRC="tm2213036d1_defa14aimg001.jpg" ALT=""></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"><IMG SRC="tm2213036d1_defa14aimg002.jpg" ALT=""></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"><IMG SRC="tm2213036d1_defa14aimg002.jpg" ALT=""><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B></B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">
    <P STYLE="font: 6pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: left">&nbsp;</P>
    <P STYLE="font: 12pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: left">3.</P></TD>
    <TD>
    <P STYLE="font: 6pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 12pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">Shareholder Proposal</P></TD>
    <TD STYLE="vertical-align: middle; text-align: center"><IMG SRC="tm2213036d1_defa14aimg002.jpg" ALT=""></TD>
    <TD STYLE="vertical-align: middle; text-align: center"><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B><IMG SRC="tm2213036d1_defa14aimg001.jpg" ALT=""></B></FONT></TD>
    <TD STYLE="vertical-align: middle; text-align: center"><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B></B><IMG SRC="tm2213036d1_defa14aimg002.jpg" ALT=""></FONT></TD></TR>
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<P STYLE="font: 16pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B></B>&nbsp;</P>

<P STYLE="font: 16pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 16pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>For questions about the proposals or how to vote
your shares </B></P>

<P STYLE="font: 14pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 16pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>please contact Okapi Partners toll-free at 877-279-2311.
</B></P>

<P STYLE="font: 14pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 16pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>PLEASE TAKE A MOMENT TO VOTE TODAY!!!</B></P>

<P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"></P>

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<P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 12pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>TEKLA LIFE SCIENCES INVESTORS</B></P>

<DIV STYLE="border-bottom: Black 1pt solid">

<P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

</DIV>

<P STYLE="font: 9pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; color: Red"><B>&nbsp;</B></P>

<P STYLE="font: 10.5pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">We want to make you aware that your clients
that hold shares in the Tekla Life Sciences Investors (the &#8220;Fund&#8221;) as of the record date of April 13, 2022, have received
proxy materials regarding the Annual Meeting of Shareholders slated for June 9, 2022.</P>

<P STYLE="font: 10.5pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10.5pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">The materials include a proxy statement with
detailed information about several proposals and a proxy card that shareholders can sign and return in a postage paid envelope. The materials
will also provide instructions on how shareholders can vote by telephone or through the Internet. You can access the materials by visiting
<FONT STYLE="color: Blue"><U>www.proxy-direct.com/TKL-32606</U></FONT>. Shareholders will be asked to vote on the following proposals.</P>

<P STYLE="font: 10.5pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10.5pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify"><B><I>The
Board of Trustees of the Fund recommends that shareholders vote FOR the election of all nominees for election as Trustees, FOR the selection
of Deloitte &amp; Touche LLP as the independent registered accountants of the Fund and <FONT STYLE="text-underline-style: double"><U STYLE="border-bottom:.5pt double; padding-bottom:.5pt">AGAINST
the shareholder proposal</U></FONT>.</I></B></P>

<P STYLE="font: 10.5pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 2pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; background-color: white; border-collapse: collapse; font-family: Arial, Helvetica, Sans-Serif">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="padding-bottom: 2pt; border-bottom: Black 1pt solid; white-space: nowrap; width: 61%">
    <P STYLE="font: 10.5pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"><B>Proposal Summary</B></P></TD>
    <TD STYLE="padding-bottom: 2pt; border-bottom: Black 1pt solid; white-space: nowrap; width: 39%">
    <P STYLE="font: 10.5pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: center"><B>RECOMMENDED VOTE</B></P></TD></TR>
  </TABLE>
<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 11pt Arial, Helvetica, Sans-Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 2pt; text-align: center; width: 3%">&nbsp;</TD>
    <TD STYLE="padding-top: 2pt"><FONT STYLE="font-size: 10pt"><B>&nbsp;</B></FONT></TD>
    <TD STYLE="padding-top: 2pt; width: 12%; text-align: center"><FONT STYLE="font-size: 10pt"><B><U>FOR ALL</U></B></FONT></TD>
    <TD STYLE="padding-top: 2pt; width: 12%; text-align: center"><FONT STYLE="font-size: 10pt"><B><U>WITHHOLD<BR>
ALL</U></B></FONT></TD>
    <TD STYLE="padding-top: 2pt; width: 12%; text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 7pt; text-align: left"><FONT STYLE="font-size: 10pt">1.</FONT></TD>
    <TD STYLE="padding-bottom: 7pt">
    <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">Election of Trustees &#8211; 1.1 &#8211; Rakesh K. Jain, Ph.D.</P>
    <P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-left: 1.38in; text-align: left; margin-top: 0pt; margin-bottom: 0pt">1.2 &#8211; Thomas M. Kent, CPA</P>
    <P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-indent: 1.75in">&nbsp;</P></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B></B><IMG SRC="tm2213036d1_defa14aimg001.jpg" ALT=""></FONT></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"><IMG SRC="tm2213036d1_defa14aimg002.jpg" ALT=""><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B></B></FONT></TD>
    <TD STYLE="padding-bottom: 7pt; text-align: center">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 7pt; text-align: center">&nbsp;</TD>
    <TD STYLE="padding-bottom: 7pt">&nbsp;</TD>
    <TD STYLE="padding-bottom: 7pt; text-align: center"><FONT STYLE="font-size: 10pt"><B><U>FOR</U></B></FONT></TD>
    <TD STYLE="padding-bottom: 7pt; text-align: center"><FONT STYLE="font-size: 10pt"><B><U>AGAINST</U></B></FONT></TD>
    <TD STYLE="padding-bottom: 7pt; text-align: center"><FONT STYLE="font-size: 10pt"><B><U>ABSTAIN</U></B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 7pt"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD STYLE="padding-bottom: 7pt"><FONT STYLE="font-size: 10pt">The ratification or rejection of the selection of Deloitte &amp; Touche LLP as the independent registered public accountants of the Fund for the fiscal year ending September 30, 2022.</FONT></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"><IMG SRC="tm2213036d1_defa14aimg001.jpg" ALT=""><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B></B></FONT></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B><IMG SRC="tm2213036d1_defa14aimg002.jpg" ALT=""></B></FONT></TD>
    <TD STYLE="padding-bottom: 7pt; vertical-align: middle; text-align: center"><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B></B></FONT><IMG SRC="tm2213036d1_defa14aimg002.jpg" ALT=""></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD><FONT STYLE="font-size: 10pt">Shareholder proposal requesting that the Fund take the steps necessary to reorganize the Board of Trustees into one class with each Trustee subject to election each year, if properly presented at the meeting.</FONT></TD>
    <TD STYLE="vertical-align: middle; text-align: center"><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B></B><IMG SRC="tm2213036d1_defa14aimg002.jpg" ALT=""></FONT></TD>
    <TD STYLE="vertical-align: middle; text-align: center"><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"></FONT><IMG SRC="tm2213036d1_defa14aimg001.jpg" ALT=""></TD>
    <TD STYLE="vertical-align: middle; text-align: center"><FONT STYLE="font-family: Sans-Serif; font-size: 9pt; color: Red"><B></B></FONT><IMG SRC="tm2213036d1_defa14aimg002.jpg" ALT=""></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0in"><B>&nbsp;</B></P>

<P STYLE="font: 10.5pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0in"><B><U>Please note that your
clients may receive a telephone solicitation in connection with this Annual Meeting from Okapi Partners, the Fund&#8217;s proxy solicitor</U>.</B>
However, we are committed to helping you maintain your client relationships while we carry out our solicitation process.&nbsp; To that
end, we are asking for your support and assistance in answering any questions you may receive from your clients on this matter.</P>

<P STYLE="font: 10.5pt Arial, Helvetica, Sans-Serif; margin: 0pt 0; text-align: justify; text-indent: 0in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol; font-size: 10.5pt">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10.5pt"><B><U>Please ask your clients
to vote as soon as possible</U>.</B> Instructions on how they can vote, over the phone, by internet or by mail will be detailed on the
proxy card they receive. </FONT></TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Arial, Helvetica, Sans-Serif">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol; font-size: 10.5pt">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10.5pt"><B><U>If
                                            you have discretion to vote on behalf of your clients</U>, </B>we can take direction via
                                            email from you and get your client&#8217;s shares voted quickly and easily, provided they
                                            are listed in Okapi&#8217;s database. All we would need is an email sent to <FONT STYLE="color: Blue"><U>HQL@okapipartners.com
                                            </U></FONT>stating &#8220;I am authorized to vote on the listed accounts&#8221;, and how
                                            you would like those shares voted. For example, &#8220;Vote with the Board&#8217;s Recommendation
                                            for all proposals&#8221;. We would just need a spreadsheet with clients&#8217; names and
                                            addresses. </FONT></TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Arial, Helvetica, Sans-Serif">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol; font-size: 10.5pt">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10.5pt"><B><U>If
                                            you do not have discretion to vote on behalf of your clients</U></B>, we can also take the
                                            same voting directions via email directly from your client (also provided they are listed
                                            in Okapi&#8217;s database). Please have them e-mail <FONT STYLE="color: Blue"><U>HQL@okapipartners.com</U></FONT>,
                                            confirming their name, address and the direction of their vote. </FONT></TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Arial, Helvetica, Sans-Serif">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol; font-size: 10.5pt">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10.5pt"><B><U>If your clients are not
in the Okapi database</U></B>, they can vote via phone, internet, or mail if they have their proxy card. If they do not have their proxy
card, Okapi will work with the shareholder to ensure they can vote their shares</FONT></TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Arial, Helvetica, Sans-Serif">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol; font-size: 10.5pt">&middot;</FONT></TD><TD STYLE="text-align: justify"><FONT STYLE="font-family: Arial, Helvetica, Sans-Serif; font-size: 10.5pt"><B><U>If you or your clients
have any questions, please provide this toll-free number for more information</U></B>: <FONT STYLE="color: red"><B>1-877-279-2311</B></FONT><B>.</B>
Agents are available to answer questions or to record voting instructions Monday through Friday from 9:00 a.m. to 9:00 p.m. Eastern Time.
The voting process is quick and easy and will require only a couple minutes of their time. </FONT></TD></TR></TABLE>

<P STYLE="margin-top: 0pt; margin-bottom: 0pt; font: 10pt Arial, Helvetica, Sans-Serif">&nbsp;</P>

<P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt"></P>

<!-- Field: Page; Sequence: 2 -->
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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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<P STYLE="font: 10pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>

<P STYLE="font: 11.04pt Arial, Helvetica, Sans-Serif; margin-top: 0pt; margin-bottom: 0pt">Telephonic Message 1</P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">This is Dan Omstead, President and Portfolio Manager of Tekla Life Sciences
Investors. We recently sent you proxy materials for this year&rsquo;s Annual Meeting of Shareholders on June 9<SUP>th</SUP>, but have
not yet received your vote. I am asking you to please vote your shares as soon as possible. There is a detailed explanation of the Board&rsquo;s
views in the materials that were sent but, in summary, the Board recommends you vote AGAINST Proposal 3, a shareholder proposal that in
their opinion is not in the best interests of long-term Fund shareholders, and FOR Proposals 1 and 2. To quickly vote your shares or if
you have any questions, please call our proxy firm, Okapi Partners, toll-free at 877-279-2311. Again, that is 877-279-2311. Thank you
in advance for your assistance with this matter and for your continued support of the Fund.</P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"></P>

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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">Telephonic Message 2</P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">This is Dan Omstead, President and Portfolio Manager of Tekla Life Sciences
Investors. I am reaching out about this year&rsquo;s Annual Meeting of shareholders which is scheduled for June 9<SUP>th</SUP>. You should
soon be receiving materials regarding the meeting and I am asking you to please vote your shares as soon as you receive them. The Fund
needs your support. In addition to manangement proposals, there is a shareholder proposal that, in the Board&rsquo;s opinion, is not in
the best interests of long-term Fund shareholders. To quickly vote your shares or if you have any questions, please call our proxy firm,
Okapi Partners, toll-free at 877-279-2311. Again, that is 877-279-2311. Thank you in advance for your assistance with this matter and
for your continued support of the Fund.</P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0"></P>

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<P STYLE="font: 11pt Arial, Helvetica, Sans-Serif; margin: 0pt 0">&nbsp;</P>

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