<SEC-DOCUMENT>0001104659-22-084121-index.html : 20220729
<SEC-HEADER>0001104659-22-084121.hdr.sgml : 20220729
<ACCEPTANCE-DATETIME>20220729135916
ACCESSION NUMBER:		0001104659-22-084121
CONFORMED SUBMISSION TYPE:	POS EX
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20220729
DATE AS OF CHANGE:		20220729
EFFECTIVENESS DATE:		20220729

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TEKLA LIFE SCIENCES INVESTORS
		CENTRAL INDEX KEY:			0000884121
		IRS NUMBER:				043147016
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		POS EX
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-195326
		FILM NUMBER:		221119853

	BUSINESS ADDRESS:	
		STREET 1:		100 FEDERAL STREET
		STREET 2:		19TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110
		BUSINESS PHONE:		6177728515

	MAIL ADDRESS:	
		STREET 1:		100 FEDERAL STREET
		STREET 2:		19TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02110

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	H&Q LIFE SCIENCES INVESTORS
		DATE OF NAME CHANGE:	19920929
</SEC-HEADER>
<DOCUMENT>
<TYPE>POS EX
<SEQUENCE>1
<FILENAME>tm2221745d2_posex.htm
<DESCRIPTION>POS EX
<TEXT>
Document 1 - file: tm2221745d2_posex.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(A)(XXI)
<SEQUENCE>2
<FILENAME>tm2221745d2_ex99axxi.htm
<DESCRIPTION>EXHIBIT 99.(A)(XXI)
<TEXT>
Document 2 - file: tm2221745d2_ex99axxi.htm

</DOCUMENT>
</SEC-DOCUMENT>