<SEC-DOCUMENT>0001752724-23-250948.txt : 20231115
<SEC-HEADER>0001752724-23-250948.hdr.sgml : 20231115
<ACCEPTANCE-DATETIME>20231115151327
ACCESSION NUMBER:		0001752724-23-250948
CONFORMED SUBMISSION TYPE:	NPORT-P
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20230930
FILED AS OF DATE:		20231115
DATE AS OF CHANGE:		20231115
PERIOD START:           	20230930

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			abrdn Life Sciences Investors
		CENTRAL INDEX KEY:			0000884121
		IRS NUMBER:				043147016
		STATE OF INCORPORATION:			PA
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		NPORT-P
		SEC ACT:		1940 Act
		SEC FILE NUMBER:	811-06565
		FILM NUMBER:		231410266

	BUSINESS ADDRESS:	
		STREET 1:		1900 MARKET STREET
		STREET 2:		SUITE 200
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19103
		BUSINESS PHONE:		6177728515

	MAIL ADDRESS:	
		STREET 1:		1900 MARKET STREET
		STREET 2:		SUITE 200
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19103

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TEKLA LIFE SCIENCES INVESTORS
		DATE OF NAME CHANGE:	20141015

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	H&Q LIFE SCIENCES INVESTORS
		DATE OF NAME CHANGE:	19920929
</SEC-HEADER>
<DOCUMENT>
<TYPE>NPORT-P
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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        <name>Ascendis Pharma A/S</name>
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      <invstOrSec>
        <name>Intellia Therapeutics Inc</name>
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      <invstOrSec>
        <name>Marinus Pharmaceuticals Inc</name>
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      <invstOrSec>
        <name>Apellis Pharmaceuticals Inc</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Biogen Inc</name>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Madrigal Pharmaceuticals Inc</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>FUSION PHARMACEUTICALS, INC.</name>
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        <fairValLevel>2</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>United Therapeutics Corp</name>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        <name>IQVIA Holdings Inc</name>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        <name>Endo International PLC</name>
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        <assetCat>EC</assetCat>
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        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Moderna Inc</name>
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        <fairValLevel>1</fairValLevel>
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        <name>HIBERCELL, INC. SERIES B</name>
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        <name>AstraZeneca PLC</name>
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        <name>AMOLYT PHARMA SAS</name>
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        <name>Incendia Therapeutics, Inc.</name>
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        <name>CRISPR Therapeutics AG</name>
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        <name>Denali Therapeutics Inc</name>
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        <name>Illumina Inc</name>
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        <name>Sutro Biopharma Inc</name>
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        <name>INVETX, INC.</name>
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        <name>Mirati Therapeutics Inc</name>
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        <name>Nkarta Inc</name>
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        <name>ABCURO, INC.</name>
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        <name>Akero Therapeutics Inc</name>
        <lei>549300SI3KG74LBE2955</lei>
        <title>Akero Therapeutics Inc</title>
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        <name>ARCA biopharma Inc</name>
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      <invstOrSec>
        <name>Tarsus Pharmaceuticals Inc</name>
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        <name>Guardant Health Inc</name>
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        <name>Oculis Holding AG</name>
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        <name>Theseus Pharmaceuticals Inc</name>
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        <name>Amgen Inc</name>
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        <name>ENDEAVOR BIOMEDICINES, INC.</name>
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        <name>Karuna Therapeutics Inc</name>
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        <name>Medpace Holdings Inc</name>
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        <name>Vaxcyte Inc</name>
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        <name>Bridgebio Pharma Inc</name>
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        <name>Fixed Income Clearing Corp</name>
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        <name>iTeos Therapeutics Inc</name>
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        <title>iTeos Therapeutics Inc</title>
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        <name>Ardelyx Inc</name>
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      <invstOrSec>
        <name>Jazz Pharmaceuticals PLC</name>
        <lei>635400GAUMJCLEZRRV50</lei>
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        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Edgewise Therapeutics Inc</name>
        <lei>N/A</lei>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Sarepta Therapeutics Inc</name>
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      <invstOrSec>
        <name>Argenx SE</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>INNOVACARE INC</name>
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        <name>TETRAPHASE PHARMACEUTICALS INC</name>
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      <invstOrSec>
        <name>DYNACURE</name>
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      <invstOrSec>
        <name>Fusion Pharmaceuticals Inc</name>
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        <assetCat>EC</assetCat>
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        <invCountry>CA</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>I-Mab</name>
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        <assetCat>EC</assetCat>
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        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Assertio Holdings Inc</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Ultragenyx Pharmaceutical Inc</name>
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        <fairValLevel>1</fairValLevel>
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        <name>Arcus Biosciences Inc</name>
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        <name>Corbus Pharmaceuticals Holdings Inc</name>
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        <name>INVETX, INC.</name>
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        <name>THERACHON MILESTONE INTEREST</name>
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        <name>Arcutis Biotherapeutics Inc</name>
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        <name>BeiGene Ltd</name>
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        <name>Altimmune Inc</name>
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        <name>ALX Oncology Holdings Inc</name>
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        <name>Natera Inc</name>
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        <name>Neurocrine Biosciences Inc</name>
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        <name>Exelixis Inc</name>
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        <name>AMPHIVENA MILESTONE INTEREST</name>
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        <name>HIBERCELL, INC. SERIES C</name>
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        <name>Alkermes PLC</name>
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        <name>Codexis Inc</name>
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        <name>89bio Inc</name>
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        <name>uniQure NV</name>
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        <name>Cercacor Laboratories Inc</name>
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        <name>Roivant Sciences Ltd</name>
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        <curCd>USD</curCd>
        <valUSD>3511381.76000000</valUSD>
        <pctVal>0.873642566447</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BM</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Fulcrum Therapeutics Inc</name>
        <lei>N/A</lei>
        <title>Fulcrum Therapeutics Inc</title>
        <cusip>359616109</cusip>
        <identifiers>
          <isin value="US3596161097"/>
        </identifiers>
        <balance>256888.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1140582.72000000</valUSD>
        <pctVal>0.283780483824</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Xencor Inc</name>
        <lei>549300V5IF65437JKG30</lei>
        <title>Xencor Inc</title>
        <cusip>98401F105</cusip>
        <identifiers>
          <isin value="US98401F1057"/>
        </identifiers>
        <balance>33240.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>669786.00000000</valUSD>
        <pctVal>0.166644813923</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNEID, INC. SERIES A</name>
        <lei>N/A</lei>
        <title>IMMUNEID, INC. SERIES A</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal Identifier" value="942RVA907"/>
        </identifiers>
        <balance>480000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>229680.00000000</valUSD>
        <pctVal>0.057145089419</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Black Diamond Therapeutics Inc</name>
        <lei>N/A</lei>
        <title>Black Diamond Therapeutics Inc</title>
        <cusip>09203E105</cusip>
        <identifiers>
          <isin value="US09203E1055"/>
        </identifiers>
        <balance>41586.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>119351.82000000</valUSD>
        <pctVal>0.029695099383</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Gilead Sciences Inc</name>
        <lei>549300WTZWR07K8MNV44</lei>
        <title>Gilead Sciences Inc</title>
        <cusip>375558103</cusip>
        <identifiers>
          <isin value="US3755581036"/>
        </identifiers>
        <balance>370811.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>27788576.34000000</valUSD>
        <pctVal>6.913883140866</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Zentalis Pharmaceuticals Inc</name>
        <lei>N/A</lei>
        <title>Zentalis Pharmaceuticals Inc</title>
        <cusip>98943L107</cusip>
        <identifiers>
          <isin value="US98943L1070"/>
        </identifiers>
        <balance>40156.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>805529.36000000</valUSD>
        <pctVal>0.200418178802</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>

    </explntrNotes>
    <signature>
      <ncom:dateSigned>2023-10-19</ncom:dateSigned>
      <ncom:nameOfApplicant>TEKLA LIFE SCIENCES INVESTORS</ncom:nameOfApplicant>
      <ncom:signature>Laura Woodward</ncom:signature>
      <ncom:signerName>Laura Woodward</ncom:signerName>
      <ncom:title>CCO</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
