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Income Taxes (Tables)

12 Months Ended

Dec. 31, 2024

Income Tax Disclosure [Abstract]

Schedule of Domestic and Foreign Components of Income (Loss) before Income Taxes

The following table presents domestic and foreign components of income (loss) before income taxes for the periods presented (in thousands):

		December 31,
		2024				2023
United States		$	(129,865	)		$	(116,798	)
Foreign			—				—
		$	(129,865	)		$	(116,798	)

Schedule of Effective Income Tax Rate Reconciliation

A reconciliation of the statutory U.S. federal rate and effective rate is as follows:

		December 31,
		2024				2023
Federal tax			21.0	%			21.0	%
State tax			—				—
Stock-based compensation			(1.4	)			(0.9	)
Research and development tax credit			1.9				2.4
Foreign losses not benefited			—				—
Global intangible low-taxed income			—				—
Change in valuation allowance			(21.5	)			(22.4	)
Other			—				(0.1	)
Income tax expense			—	%			—	%

Schedule of Components of Deferred Tax Assets and Liabilities

The components of the Company’s deferred tax assets and liabilities are as follows (in thousands):

		December 31,
		2024				2023
Deferred tax assets:
Net operating loss carryforwards		$	67,565			$	58,248
Federal and state research and development tax credits			15,086				12,601
Accrued liabilities and reserves			1,355				1,234
Stock-based compensation			8,588				6,238
Depreciation and amortization			8,036				689
Lease liability			944				1,450
Research and development capitalized expenditures			33,708				27,290
Gross deferred tax assets			135,282				107,750
Valuation allowance			(134,582	)			(106,652	)
Deferred tax liabilities:
Right of use asset			(700	)			(1,098	)
Other			—				—
Gross deferred tax liabilities			(700	)			(1,098	)
Net deferred taxes		$	—			$	—

Schedule of Reconciliation of Unrecognized Tax Benefits

A reconciliation of the beginning and ending amounts of unrecognized tax benefits for the years ended December 31, 2024 and 2023 resulting primarily from research and development tax credits claimed for both U.S. and foreign operations on the Company’s annual tax returns were as follows (in thousands):

		December 31,
		2024				2023
Balance at beginning of year		$	4,674			$	3,663
Additions on tax positions related to prior years			—				(3	)
Additions on tax positions related to current year			905				1,014
Balance at end of year		$	5,579			$	4,674

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Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

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Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

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Tabular disclosure of income before income tax between domestic and foreign jurisdictions.

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Tabular disclosure of the change in unrecognized tax benefits.

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