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Commitments - Additional Information (Details)
 1 Months Ended 12 Months Ended
Nov. 30, 2022
ft²
Apr. 30, 2018
ft²
May 31, 2015
ft²
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Lessee Lease Description [Line Items]          
Contingency losses, accrued | $       $ 0 $ 0
Lease expiration period 2025-07        
Additional laboratory and office facilities under lease | ft²   6,378      
Increased of leased premises | ft²   36,754      
Lessee operating lease extended lease term   2026-11      
Lease existence of option to extend true   true    
Lessee operating lease option to extend 6 months   5 years    
Lease expense | $       2,300,000 2,300,000
Rent expense | $       3,100,000 $ 2,900,000
Cash paid for operating lease liabilities | $       $ 2,900,000  
Operating lease, weighted average remaining lease term       1 year 8 months 19 days  
Operating lease, weighted average discount rate, percent       8.21%  
South San Francisco and California          
Lessee Lease Description [Line Items]          
Laboratory and office facilities under lease | ft²     30,376    
Additional office facilities under lease | ft² 13,232