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<!--Generated by DFIN XBRL Instance Document - http://www.dfinsolutions.com/ - Version R3.0 - on 25-March-2023 [08:06:05] {AM}-->
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<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_cyh_TimHingtgenMember" xml:lang="en-US">Tim Hingtgen [Member]</label>
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<loc xlink:type="locator" xlink:href="cyh-20221231.xsd#cyh_WayneSmithMember" xlink:label="loc_cyh_WayneSmithMember" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_cyh_WayneSmithMember" xml:lang="en-US">Wayne Smith [Member]</label>
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<loc xlink:type="locator" xlink:href="cyh-20221231.xsd#cyh_StockAndOptionAwardValuesReportedInTheSctMember" xlink:label="loc_cyh_StockAndOptionAwardValuesReportedInTheSctMember" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_cyh_StockAndOptionAwardValuesReportedInTheSctMember" xml:lang="en-US">Stock and Option Award values reported in the SCT [Member]</label>
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<loc xlink:type="locator" xlink:href="cyh-20221231.xsd#cyh_FairValueOfStockAndOptionAwardsGrantedDuringTheCoveredYearMember" xlink:label="loc_cyh_FairValueOfStockAndOptionAwardsGrantedDuringTheCoveredYearMember" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_cyh_FairValueOfStockAndOptionAwardsGrantedDuringTheCoveredYearMember" xml:lang="en-US">Fair Value of Stock and Option Awards Granted during the Covered Year [Member]</label>
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<loc xlink:type="locator" xlink:href="cyh-20221231.xsd#cyh_ChangeInFairValueOfOutstandingUnvestedStockAndOptionAwardsFromPriorYearsMember" xlink:label="loc_cyh_ChangeInFairValueOfOutstandingUnvestedStockAndOptionAwardsFromPriorYearsMember" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_cyh_ChangeInFairValueOfOutstandingUnvestedStockAndOptionAwardsFromPriorYearsMember" xml:lang="en-US">Change in Fair Value of Outstanding Unvested Stock and Option Awards from Prior Years [Member]</label>
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<loc xlink:type="locator" xlink:href="cyh-20221231.xsd#cyh_ChangeInFairValueOfStockAndOptionAwardsFromPriorYearsThatVestedInTheCoveredYearMember" xlink:label="loc_cyh_ChangeInFairValueOfStockAndOptionAwardsFromPriorYearsThatVestedInTheCoveredYearMember" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_cyh_ChangeInFairValueOfStockAndOptionAwardsFromPriorYearsThatVestedInTheCoveredYearMember" xml:lang="en-US">Change in Fair Value of Stock and Option Awards from Prior Years that Vested in the Covered Year [Member]</label>
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<loc xlink:type="locator" xlink:href="cyh-20221231.xsd#cyh_FairValueOfStockAndOptionAwardsForfeitedDuringTheCoveredYearMember" xlink:label="loc_cyh_FairValueOfStockAndOptionAwardsForfeitedDuringTheCoveredYearMember" />
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<loc xlink:type="locator" xlink:href="cyh-20221231.xsd#cyh_AggregateChangeInActuarialPresentValueOfDefinedBenefitPlansMember" xlink:label="loc_cyh_AggregateChangeInActuarialPresentValueOfDefinedBenefitPlansMember" />
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<loc xlink:type="locator" xlink:href="cyh-20221231.xsd#cyh_AggregateServiceCostAndPriorServiceCostForPensionPlansMember" xlink:label="loc_cyh_AggregateServiceCostAndPriorServiceCostForPensionPlansMember" />
<label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="lab_cyh_AggregateServiceCostAndPriorServiceCostForPensionPlansMember" xml:lang="en-US">Aggregate Service Cost and Prior Service Cost for Pension Plans [Member]</label>
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