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Income Taxes (Tables) | 3 Months Ended
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Mar. 31, 2018
Income Tax Disclosure [Abstract] |
Reconciliation of effective tax rate to the U.S. federal statutory tax rate | A reconciliation of the U.S. federal statutory tax rate to the Company’s effective income tax rate is as follows:
| Three months ended March 31,
| 2018 |  | 2017
U.S. federal statutory tax rate | (21.0 | )% |  | (35.0 | )%
State income taxes, net of federal benefit | (37.0 | ) |  | (2.2 | )
Non-U.S. income taxed at different rates | 102.0 |  |  | 0.5 |
Reduction in tax benefit related to stock-based awards | (217.7 | ) |  | 6.2 |
Non-deductible expenses | (44.2 | ) |  | (0.7 | )
Research and development credit | 132.1 |  |  | 1.1 |
Other | (15.1 | ) |  | — |
Effective income tax rate | (100.9 | )% |  | (30.1 | )%

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- Definition Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32687-109319 + Details
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