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Income Taxes - Reconciliation of Effective Tax Rate (Details)
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Income Tax Disclosure [Abstract]        
U.S. federal statutory tax rate (21.00%) (35.00%) (21.00%) (35.00%)
State income taxes, net of federal benefit 6.00% (4.80%) 0.50% (3.80%)
Non-U.S. income taxed at different rates (15.30%) (0.10%) (0.40%) 0.10%
Reduction in tax benefit related to stock-based awards 33.50% 13.40% 1.40% 10.70%
Non-deductible expenses 18.30% (1.50%) 10.40% (1.20%)
Research and development credit (20.20%) 2.60% (0.80%) 2.00%
Valuation allowance 43.90% 0.10% 36.40% 0.10%
Other 0.20% (3.00%) 0.20% (1.90%)
Effective income tax rate 45.40% (28.30%) 26.70% (29.00%)