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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Cash flows from operating activities:    
Net loss $ (44,444,888) $ (42,985,123)
Adjustment to reconcile to net loss to net cash used in operating activities:    
Depreciation and amortization expense 248,628 269,691
Reduction in carrying amount of right-of-use assets 255,660 247,165
Intangible asset amortization 21,950 21,950
Stock-based compensation expense 4,673,290 4,776,623
Net accretion of discount on marketable securities 0 (203,491)
Loss on disposal of fixed assets 0 1,315
(Increase) decrease in:    
Prepaid expenses and other current assets 1,904,097 (1,183,785)
Other assets 802,848 (261,337)
Increase (decrease) in:    
Accounts payable (474,214) (168,884)
Accrued expenses 1,908,736 (581,135)
Lease liabilities (246,528) (221,934)
Other liabilities (153,576) (200,113)
Net cash used in operating activities (35,503,997) (40,489,058)
Cash flows from investing activities:    
Purchases of property and equipment (18,316) (75,519)
Purchases of marketable securities 0 (5,410,170)
Maturities of marketable securities 0 26,430,000
Net cash (used in) provided by investing activities (18,316) 20,944,311
Cash flows from financing activities:    
Proceeds from exercise of stock options 138,700 732,458
Proceeds from issuance of common stock under employee stock purchase plan 421,910 374,652
Proceeds from issuance of common stock through private placement with Aventis Inc 25,000,000 0
Payment of offering and placement costs (3,138,911) 0
Net cash provided by financing activities 226,940,670 5,344,507
Net increase (decrease) in cash and cash equivalents 191,418,357 (14,200,240)
Cash and cash equivalents at beginning of period 36,144,720 59,405,817
Cash and cash equivalents at end of period 227,563,077 45,205,577
Supplemental disclosures of noncash information:    
Offering and placement costs included in accounts payable/accrued expenses 845,933 0
At-the-market offering    
Cash flows from financing activities:    
Proceeds from issuance of common stock under at-the-market offering, net of issuance costs 15,020,046 4,237,397
Warrant    
Cash flows from financing activities:    
Proceeds from issuance of common stock under at-the-market offering, net of issuance costs 24,998,919 0
Public Offering    
Cash flows from financing activities:    
Proceeds from issuance of common stock under at-the-market offering, net of issuance costs 164,500,006 $ 0
Private Placement    
Cash flows from financing activities:    
Payment of offering and placement costs $ (1,600,000)