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v3.10.0.1

Consolidated Statement of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Sep. 30, 2018 | Sep. 30, 2017 | Sep. 30, 2016
Cash flows from operating activities: |  |  |
Net loss | $ (44,751) | $ (19,727) | $ (12,550)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation | 1,709 | 1,009 | 478
Loss on disposal of fixed assets | 8 | 0 | 0
Non-cash share-based compensation | 6,765 | 3,153 | 2,257
Non-cash consideration for licenses | 0 | 0 | 1,199
Changes in operating assets and liabilities |  |  |
Prepaid expenses and other current assets | (7,132) | (2,317) | (2,048)
Accounts payable | 838 | 434 | 507
Accrued expenses and other liabilities | 11,026 | 1,088 | 308
Net cash used in operating activities | (31,537) | (16,360) | (9,849)
Cash flows from investing activities: |  |  |
Purchases of property and equipment | (9,119) | (2,876) | (1,855)
Purchase of intangible assets | (412) | 0 | 0
Net cash used in investing activities | (9,531) | (2,876) | (1,855)
Cash flows from financing activities: |  |  |
Proceeds of issuance of ordinary shares, net of issuance costs | 156,920 | 127,686 | 32,222
Net cash provided by financing activities | 156,920 | 127,686 | 32,222
Effect of exchange rate changes on cash | (5,833) | 561 | (2,662)
Net increase in cash | 110,019 | 109,011 | 17,856
Cash, beginning of year | 137,070 | 28,059 | 10,203
Cash, end of year | 247,089 | 137,070 | 28,059
Supplemental Cash Flow Information |  |  |
Property and equipment purchases included in accounts payable | $ 328 | $ 0 | $ 0

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