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Share Based Compensation (Tables)
 12 Months Ended
Sep. 30, 2018
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of Stock Options Valuation Assumptions
The assumptions (see Note 2) used in the Black-Scholes option pricing model to determine the fair value of the share options granted to employees and directors during the year ended September 30, 2018 and 2017 were as follows:

 
September 30,
 
2018
 
2017
Expected option life (years)
6 years
 
6 years
Risk-free interest rate
2.61% to 3.00%
 
1.91% to 2.05%
Expected volatility
68.15% to 72.99%
 
68.61% to 68.93%
Expected dividend yield
0.00%
 
0.00%
Stock Option Rollforward
The table below reflects the conversion of ordinary shares in the current and previous years.
 
 
 
Number of
Options
 
Weighted-
Average
Exercise
Price
 
Weighted-
Average
Remaining
Contractual
Term
(Years)
 
Aggregate
Intrinsic
Value
Outstanding as of September 30, 2016
 
—

 
$
—

 
—

 
$
—

Granted
 
570,537

 
0.51

 
—

 
—

Exercised
 
—

 
—

 
—

 
—

Canceled or forfeited
 
(228
)
 
0.00

 
—

 
—

Outstanding as of September 30, 2017
 
570,309

 
$
0.51

 
9.73

 
$
2,024

Granted
 
1,513,218

 
$
13.33

 
—

 
—

Exercised
 
—

 
—

 
—

 
—

Canceled or forfeited
 
(18,046
)
 
$
4.99

 
—

 
—

Outstanding as of September 30, 2018
 
2,065,481

 
$
9.87

 
9.35

 
$
43,146

Exercisable as of September 30, 2018
 
166,262

 
$
0.52

 
8.73

 
$
5,022

Vested and expected to vest as of September 30, 2018
 
2,065,481

 
$
9.87

 
9.35

 
$
43,146
Schedule of Nonvested Share Activity
A summary of the changes in the Company’s restricted ordinary shares during the years ended September 30, 2018 and 2017 are as follows and reflect the conversion of ordinary shares in the current and previous years.
 
 
Number of
restricted
shares
 
Weighted average 
grant date 
fair value
Unvested and outstanding at September 30, 2015
 
416,887

 
$
3.54

Granted
 
1,070,797

 
4.08

Vested
 
(220,940
)
 
3.38

Canceled or forfeited
 
(125
)
 
3.03

Unvested and outstanding at September 30, 2016
 
1,266,619

 
3.89

Granted
 
642,150

 
4.36

Vested
 
(453,134
)
 
3.92

Canceled or forfeited
 
(97,318
)
 
4.20

Unvested and outstanding at September 30, 2017
 
1,358,317

 
4.20

Granted
 
—

 
—

Vested
 
(534,906
)
 
3.96

Canceled or forfeited
 
(7,779
)
 
3.68

Unvested and outstanding at September 30, 2018
 
815,632

 
$
4.17
Schedule of Restricted Stock Valuation Assumptions
The assumptions (Note 2) used in the OPM to determine the fair value of the ordinary shares for the following dates are as follows:
 
 
March 2, 
2016
 
April 26, 
2017
 
September 25, 
2017
 
March 31, 2018
 
May 31, 2018
Expected term
 
2.8 years

 
1.2 years

 
0.8 years

 
1.8 years

 
1.8 years

Risk-free interest rate
 
1.0
%
 
1.0
%
 
1.3
%
 
2.1
%
 
2.1
%
Expected volatility
 
73.2
%
 
76.6
%
 
71.0
%
 
71
%
 
71
%
Expected dividend yield
 
0.0
%
 
0.0
%
 
0.0
%
 
0.0
%
 
0.0
%
Schedule of Allocated Share Based Compensation
Share-based compensation expense recorded as research and development and general and administrative expenses is as follows (in thousands):
 
 
 
Year ended September 30,
 
 
2018
 
2017
 
2016
Research and development
 
$
3,116

 
$
1,145

 
$
916

General and administrative
 
3,649

 
2,008

 
1,341

Total share-based compensation
 
$
6,765

 
$
3,153

 
$
2,257