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Selected Financial Data for the Three Months Ended December 31, 2017 (Details) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Dec. 31, 2018 | Dec. 31, 2017 | Sep. 30, 2018 | Sep. 30, 2017 | Sep. 30, 2016 | Sep. 30, 2015
Results of Operations |  |  |  |  |  |
Grant income | $ 296 | $ 231 | $ 1,407 | $ 1,693 | $ 1,212 |
Operating expenses: |  |  |  |  |  |
Research and development | (17,713) | (5,564) | (36,150) | (16,012) | (10,436) |
General and administrative | (7,593) | (3,084) | (22,790) | (9,099) | (5,152) |
Total operating expenses, net | (25,010) | (8,417) | (57,533) | (23,418) | (14,376) |
Other income (expense): |  |  |  |  |  |
Interest income | 660 | 181 | 1,532 | 84 | 75 |
Other income (expense) | 1,097 | (685) | 3,970 | (46) | (26) |
Total other income, net | 1,757 | (504) | 5,502 | 38 | 49 |
Net loss before income tax | (23,253) | (8,921) | (52,031) | (23,380) | (14,327) |
Income tax benefit | 2,605 | 1,397 | 7,280 | 3,653 | 1,777 |
Net loss attributable to ordinary shareholders | (20,648) | (7,524) | (44,751) | (19,727) | (12,550) |
Cash Flows |  |  |  |  |  |
Net cash used in operating activities | (19,785) | (8,797) | (31,537) | (16,360) | (9,849) |
Net cash used in investing activities | (4,422) | (764) | (9,531) | (2,876) | (1,855) |
Net cash provided by financing activities | 0 | 433 | 156,920 | 127,686 | 32,222 |
Effect of exchange rate changes on cash |  | 1,042 |  |  |  |
Net decrease in cash |  | (8,086) |  |  |  |
Balance Sheet Data |  |  |  |  |  |
Cash | 217,450 | 128,984 | 246,984 | 137,070 | 28,059 |
Working capital |  | 131,576 |  |  |  |
Net assets |  | 137,515 |  |  |  |
Total assets | 254,210 | 142,715 | 273,205 | 148,662 |  |
Ordinary shares |  | 1 |  |  |  |
Additional paid-in capital | 361,311 | 195,644 | 357,918 | 194,351 |  |
Total shareholders' equity | $ 232,642 | $ 137,515 | $ 255,465 | $ 142,601 | $ 30,687 | $ 10,501

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