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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Cash flows from operating activities:    
Net loss $ (33,266,000) $ (29,873,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,662,000 1,261,000
Share-based compensation (net of amount capitalized) (670,000) 6,189,000
Loss (gain) on termination of operating lease 11,000 (160,000)
Loss on disposal of property and equipment 672,000 0
Deferred income tax (280,000) 0
Changes in operating assets and liabilities    
Prepaid expenses and other assets, current (5,050,000) (1,186,000)
Prepaid expenses and other assets, non-current 163,000 (233,000)
Long-term deposits 811,000 (18,000)
Right of use assets, net 1,085,000 769,000
Accounts payable (902,000) (124,000)
Accrued expenses and other liabilities (1,649,000) (361,000)
Lease liabilities 70,000 (297,000)
Net cash used in operating activities (37,343,000) (24,033,000)
Cash flows from investing activities:    
Purchases of property and equipment (1,900,000) (2,637,000)
Net cash used in investing activities (1,900,000) (2,637,000)
Cash flows from financing activities:    
Proceeds of issuance of ordinary shares, net of issuance costs 123,324,000 74,310,000
Net cash provided by financing activities 123,324,000 74,310,000
Effect of exchange rate changes on cash and restricted cash 1,632,000 (14,972,000)
Net increase in cash and restricted cash 85,713,000 32,668,000
Cash and restricted cash, beginning of period 154,085,000 211,430,000
Cash and restricted cash, end of period 239,798,000 244,098,000
Supplemental non-cash flow information    
Property and equipment purchases included in accounts payable and accrued expenses 569,000 4,624,000
Right of use assets terminated and obtained in exchange for operating lease liabilities, net 0 2,487,000
Capitalized implementation costs included in accrued expenses 190,000 607,000
Issuance costs included in accounts payable and accrued expenses 1,124,000 334,000
Capitalized share-based compensation 0 46,000
Lease assets terminated 28,517,000 0
Reconciliation of cash and restricted cash reported within the condensed consolidated balance sheets:    
Total cash and restricted cash $ 239,798,000 $ 244,098,000