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Condensed Consolidated Statements of Shareholders’ Equity (Unaudited) - USD ($)
$ in Thousands
Total
Common shares
Common shares
Ordinary Shares
Common shares
Deferred Shares
Common shares
Deferred B Shares
Common shares
Deferred C Shares
Additional Paid in Capital
Accumulated other comprehensive loss
Accumulated deficit
Beginning balance at Dec. 31, 2019 $ 254,839   $ 2 $ 0 $ 118 $ 0 $ 500,560 $ (8,691) $ (237,150)
Beginning balance (in shares) at Dec. 31, 2019     44,983,006 34,425 88,893,548 1      
Stockholders' Equity                  
Issuance of ordinary shares, net of issuance costs 73,953   $ 1       73,952    
Issuance of ordinary shares, net of issuance costs     7,250,000            
Share-based compensation expense 15,786           15,786    
Restricted shares - forfeited     (1,969)            
Exercise of share options 71           71    
Exercise of share options     67,839            
Unrealized gain (loss) on foreign currency translation (8,605)             (8,605)  
Net loss (99,233)               (99,233)
Ending balance at Sep. 30, 2020 236,811   $ 3 $ 0 $ 118 $ 0 590,369 (17,296) (336,383)
Ending balance (in shares) at Sep. 30, 2020     52,298,876 34,425 88,893,548 1      
Beginning balance at Jun. 30, 2020 258,952   $ 3 $ 0 $ 118 $ 0 586,110 (28,211) (299,068)
Beginning balance (in shares) at Jun. 30, 2020     52,250,404 34,425 88,893,548 1      
Stockholders' Equity                  
Share-based compensation expense 4,245           4,245    
Exercise of share options 14           14    
Exercise of share options     48,472            
Unrealized gain (loss) on foreign currency translation 10,915             10,915  
Net loss (37,315)               (37,315)
Ending balance at Sep. 30, 2020 236,811   $ 3 $ 0 $ 118 $ 0 590,369 (17,296) (336,383)
Ending balance (in shares) at Sep. 30, 2020     52,298,876 34,425 88,893,548 1      
Beginning balance at Dec. 31, 2020 210,032   $ 3 $ 0 $ 118 $ 0 595,016 (5,861) (379,244)
Beginning balance (in shares) at Dec. 31, 2020     52,346,231 34,425 88,893,548 1      
Stockholders' Equity                  
Issuance of ordinary shares, net of issuance costs 136,538           136,538    
Issuance of ordinary shares, net of issuance costs     20,216,544            
Share-based compensation expense 2,112           2,112    
Vesting of restricted stock (in shares)     163,375            
Exercise of share options $ 126           126    
Exercise of share options 192,844   192,844            
Unrealized gain (loss) on foreign currency translation $ (3,648)             (3,648)  
Net loss (100,430)               (100,430)
Ending balance at Sep. 30, 2021 244,730   $ 3 $ 0 $ 118 $ 0 733,792 (9,509) (479,674)
Ending balance (in shares) at Sep. 30, 2021     72,918,994 34,425 88,893,548 1      
Beginning balance at Jun. 30, 2021 283,682   $ 3 $ 0 $ 118 $ 0 732,290 (3,046) (445,683)
Beginning balance (in shares) at Jun. 30, 2021     72,742,582 34,425 88,893,548 1      
Stockholders' Equity                  
Share-based compensation expense 1,502           1,502    
Vesting of restricted stock (in shares)   141,875              
Exercise of share options     34,537            
Unrealized gain (loss) on foreign currency translation (6,463)             (6,463)  
Net loss (33,991)               (33,991)
Ending balance at Sep. 30, 2021 $ 244,730   $ 3 $ 0 $ 118 $ 0 $ 733,792 $ (9,509) $ (479,674)
Ending balance (in shares) at Sep. 30, 2021     72,918,994 34,425 88,893,548 1