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Property and Equipment, Net
9 Months Ended
Sep. 30, 2022
Property, Plant and Equipment [Abstract]  
Property and Equipment, Net Property and Equipment, Net
Property and equipment, net consisted of the following (in thousands):
September 30,December 31,
20222021
Lab equipment
$28,653 $34,091 
Office equipment
3,087 3,463 
Furniture and fixtures
1,124 1,363 
Leasehold improvements
12,348 14,904 
Assets under construction
11,108 2,436 
Less: accumulated depreciation and impairment
(23,846)(22,716)
Total property and equipment, net
$32,474 $33,541 

Depreciation expense for the three months ended September 30, 2022 and 2021 was $1.8 million and $2.4 million, respectively, and for the nine months ended September 30, 2022 and 2021 was $5.7 million and $6.5 million, respectively.