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Net loss per share (Tables)

9 Months Ended

Sep. 30, 2022

Earnings Per Share [Abstract]

Schedule of Earnings Per Share, Basic and Diluted

Basic and diluted net loss per share attributable to ordinary shareholders was calculated as follows (in thousands, except share and per share amounts):

			Three Months Ended September 30,												Nine Months Ended September 30,
			2022						2021						2022						2021
Numerator
Net loss			$	(42,767)					$	(33,991)					$	(121,888)					$	(100,430)
Net loss attributable to ordinary shareholders - basic and diluted			$	(42,767)					$	(33,991)					$	(121,888)					$	(100,430)
Denominator
Weighted-average number of ordinary shares used in net loss per share - basic and diluted			91,240,801						72,896,362						91,028,562						68,770,962
Net loss per share - basic and diluted			$	(0.47)					$	(0.47)					$	(1.34)					$	(1.46)

Schedule of Anti-dilutive Securities

The following potentially dilutive securities have been excluded from the calculation of diluted net loss per share due to their anti-dilutive effect:

			Three and Nine Months Ended September 30,
			2022						2021
Unvested restricted incentive shares and units			996,927						1,105,300
Share options			10,421,137						6,343,281
Warrants			3,265,306						—
Total potentially dilutive securities			14,683,370						7,448,581

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- References

No definition available.

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- Definition

Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 260
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257

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- Definition

Tabular disclosure of an entity's basic and diluted earnings per share calculations, including a reconciliation of numerators and denominators of the basic and diluted per-share computations for income from continuing operations.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 260
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257

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