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Accrued Expenses and Other Liabilities (Details) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Payables and Accruals [Abstract]
Compensation and benefits	$ 8,258	$ 8,747
Research and development costs	23,231	11,311
UCLB milestone and option	0	10
Professional fees	2,299	3,449
U.S. corporate income and local taxes	26	0
Other liabilities	855	150
Total accrued expenses and other liabilities	$ 34,669	$ 23,667

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Carrying amount as of the balance sheet date of the unpaid sum of the known and estimated amounts payable to satisfy all currently due domestic and foreign income tax obligations.

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