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Share-based Compensation Expense - Share-based Compensation Allocation (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award        
Total share-based compensation $ 3,337 $ 1,502 $ 8,599 $ 2,112
Research and development        
Share-based Compensation Arrangement by Share-based Payment Award        
Total share-based compensation 1,831 556 4,802 (238)
General and administrative        
Share-based Compensation Arrangement by Share-based Payment Award        
Total share-based compensation $ 1,506 $ 946 $ 3,797 $ 2,350