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Liability related to sales of future royalties and sales milestones, net - Schedule of Liability Related to Revenue (Details) - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Liability, Future Revenue, Rollforward [Abstract]    
Non-cash interest expense on liability related to sale of future royalties and sales milestones $ 5,427 $ 0
Blackstone Collaboration Agreement    
Liability, Future Revenue, Rollforward [Abstract]    
Balance as of December 31, 2021 47,016  
Non-cash interest expense on liability related to sale of future royalties and sales milestones 5,427  
Balance as of September 30, 2022 $ 52,443