Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 256,415	$ 382,436
Restricted cash	434	325
Prepaid expenses and other current assets	51,533	43,010
Total current assets	308,382	425,771
Non-current assets:
Property and equipment, net	34,637	35,209
Prepaid expenses and other non-current assets	136	2,176
Operating lease right-of-use assets, net	59,403	23,210
Long-term deposits	943	1,832
Deferred tax asset	2,597	2,076
Total assets	406,098	490,274
Current liabilities:
Accounts payable	661	531
Accrued expenses and other liabilities	31,388	40,797
Operating lease liabilities, current	5,491	5,038
Total current liabilities	37,540	46,366
Non-current liabilities:
Operating lease liabilities, non-current	46,967	19,218
Liability related to future royalties and sales milestones, net	140,778	125,900
Other long-term payables	295	116
Total liabilities	225,580	191,600
Commitments and contingencies
Shareholders' equity:
Additional paid-in capital	1,015,577	1,007,625
Accumulated other comprehensive loss	(33,794)	(38,898)
Accumulated deficit	(801,391)	(670,179)
Total shareholders' equity	180,518	298,674
Total liabilities and shareholders' equity	406,098	490,274
Ordinary shares
Shareholders' equity:
Share value	8	8
Deferred shares
Shareholders' equity:
Share value	0	0
Deferred B Shares
Shareholders' equity:
Share value	118	118
Deferred C Shares
Shareholders' equity:
Share value	$ 0	$ 0

Carrying value as of the balance sheet date of liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

Name:	us-gaap_AccountsPayableCurrent
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).