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Stock-based compensation (Details 2) - USD ($) | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | ---
Sep. 30, 2015 | Sep. 30, 2014 | Sep. 30, 2015 | Sep. 30, 2014 | Dec. 31, 2014
Stock options |  |  |  |  |
Outstanding at beginning of period (in shares) |  |  | 1,226,140 |  |
Granted (in shares) |  |  | 550,797 |  |
Exercised (in shares) |  |  | (25,045) |  |
Cancelled or forfeited (in shares) |  |  | (39,881) |  |
Outstanding at end of period (in shares) | 1,712,011 |  | 1,712,011 |  | 1,226,140
Exercisable at end of period (in shares) | 755,860 |  | 755,860 |  |
Vested or expected to vest at end of period (in shares) | 1,586,233 |  | 1,586,233 |  |
Weighted-Average Exercise Price |  |  |  |  |
Outstanding at beginning of period (in dollars per share) |  |  | $ 4.14 |  |
Granted (in dollars per share) |  |  | 11.69 |  |
Exercised (in dollars per share) |  |  | 2.05 |  |
Cancelled or forfeited (in dollars per share) |  |  | 5.46 |  |
Outstanding at end of period (in dollars per share) | $ 6.57 |  | 6.57 |  | $ 4.14
Exercisable at end of period (in dollars per share) | 3.27 |  | 3.27 |  |
Vested or expected to vest at end of period (in dollars per share) | $ 6.30 |  | $ 6.30 |  |
Weighted-Average Remaining Contractual Term |  |  |  |  |
Outstanding at beginning of period |  |  | 8 years 1 month 10 days |  | 8 years 1 month 24 days
Outstanding at end of period |  |  | 8 years 1 month 10 days |  | 8 years 1 month 24 days
Exercisable at end of period |  |  | 6 years 10 months 21 days |  |
Vested or expected to vest at end of period |  |  | 8 years 7 days |  |
Intrinsic Value |  |  |  |  |
Outstanding at the end of the period | $ 4,560,000 |  | $ 4,560,000 |  | $ 6,579,000
Exercisable at the end of the period | 3,659,000 |  | 3,659,000 |  |
Fair value of options vested |  |  | 4,489,000 |  |
Options to purchase Common Stock |  |  |  |  |
Intrinsic Value |  |  |  |  |
Intrinsic value of options exercised | 0 | $ 200,000 | 200,000 | $ 300,000 |
Unrecognized stock-based compensation expense |  |  |  |  |
Unrecognized compensation expense related to unvested stock option awards | $ 5,200,000 |  | $ 5,200,000 |  |
Weighted-average amortization period over which cost is expected to be recognized |  |  | 3 years 1 month 6 days |  |

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