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Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($) $ in Thousands | Series A Convertible Preferred Stock | Series B Convertible Preferred Stock | Common stock | Additional Paid-in Capital | Accumulated Deficit | Total
--- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2012 | $ 38,724 |  |  |  |  |
Balance (in shares) at Dec. 31, 2012 | 55,700,752 |  |  |  |  |
Increase (decrease) in Convertible Preferred Stock |  |  |  |  |  |
Issuance of convertible preferred stock, net of issuance costs of $82 | $ 9,174 | $ 32,248 |  |  |  |
Issuance of convertible preferred stock, net of issuance costs (in shares) | 13,136,951 | 34,129,571 |  |  |  |
Balance at Dec. 31, 2013 | $ 47,898 | $ 32,248 |  |  |  |
Balance (in shares) at Dec. 31, 2013 | 68,837,703 | 34,129,571 |  |  |  |
Balance at Dec. 31, 2012 |  |  |  | $ 942 | $ (35,378) | $ (34,436)
Balance (in shares) at Dec. 31, 2012 |  |  | 374,381 |  |  |
Increase (Decrease) in Stockholders' Equity (Deficit) |  |  |  |  |  |
Proceeds from exercises of common stock options |  |  |  | 27 |  | 27
Proceeds from exercises of common stock options (in shares) |  |  | 18,965 |  |  |
Stock-based compensation expense |  |  |  | 343 |  | 343
Net loss |  |  |  |  | (18,118) | (18,118)
Balance at Dec. 31, 2013 |  |  |  | 1,312 | (53,496) | (52,184)
Balance (in shares) at Dec. 31, 2013 |  |  | 393,346 |  |  |
Balance at Dec. 31, 2014 | $ 47,898 | $ 32,248 |  |  |  |
Balance (in shares) at Dec. 31, 2014 | 68,837,703 | 34,129,571 |  |  |  |
Increase (Decrease) in Stockholders' Equity (Deficit) |  |  |  |  |  |
Proceeds from exercises of common stock options |  |  | $ 1 | 117 |  | 118
Proceeds from exercises of common stock options (in shares) |  |  | 99,854 |  |  |
Stock-based compensation expense |  |  |  | 897 |  | 897
Net loss |  |  |  |  | (21,884) | (21,884)
Balance at Dec. 31, 2014 |  |  | $ 1 | 2,326 | (75,380) | (73,053)
Balance (in shares) at Dec. 31, 2014 |  |  | 493,200 |  |  |
Increase (decrease) in Convertible Preferred Stock |  |  |  |  |  |
Issuance of convertible preferred stock, net of issuance costs of $82 |  | $ 12,331 |  |  |  |
Issuance of convertible preferred stock, net of issuance costs (in shares) |  | 13,062,965 |  |  |  |
Conversion of Convertible preferred stock to common stock | $ (47,898) | $ (44,579) |  |  |  | (92,477)
Conversion of Convertible preferred stock to common stock (in shares) | (68,837,703) | (47,192,536) |  |  |  |
Balance (in shares) at Dec. 31, 2015 | 0 | 0 |  |  |  |
Increase (Decrease) in Stockholders' Equity (Deficit) |  |  |  |  |  |
Initial public offering, net of issuance costs of $7.3 million |  |  | $ 5 | 61,739 |  | 61,744
Initial public offering, net of issuance costs of $7.3 million (in shares) |  |  | 5,750,000 |  |  |
Proceeds from exercises of common stock options |  |  |  | 91 |  | $ 91
Proceeds from exercises of common stock options (in shares) |  |  | 40,548 |  |  | 40,548
Stock-based compensation expense |  |  |  | 1,658 |  | $ 1,658
Conversion of convertible preferred stock into common stock |  |  | $ 9 | 92,468 |  | 92,477
Conversion of convertible preferred stock into common stock (in shares) |  |  | 9,029,549 |  |  |
Conversion of preferred stock warrants into warrants for the purchase of common stock |  |  |  | 206 |  | 206
Net loss |  |  |  |  | (32,630) | (32,630)
Balance at Dec. 31, 2015 |  |  | $ 15 | $ 158,488 | $ (108,010) | $ 50,493
Balance (in shares) at Dec. 31, 2015 |  |  | 15,313,297 |  |  |

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