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Summary of Significant Accounting Polices - Warrants thru Stock-Based Compensation (Details) - USD ($) $ / shares in Units, shares in Millions | 12 Months Ended |
--- | --- | ---
Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013 | Dec. 31, 2010
Warrants |  |  |  |
Warrants outstanding | 0.0 | 0.1 |  |
Exercise price of warrants (in dollars per share) |  |  |  | $ 1.67
Assets: |  |  |  |
Money market fund | $ 62,004,000 | $ 13,506,000 |  |
Liabilities: |  |  |  |
Liability | 0 |  |  |
Stock based compensation |  |  |  |
Stock-based compensation expense | 1,658,000 | 897,000 | $ 343,000 |
Research and development |  |  |  |
Stock based compensation |  |  |  |
Stock-based compensation expense | 681,000 | 434,000 | 224,000 |
General and administrative |  |  |  |
Stock based compensation |  |  |  |
Stock-based compensation expense | 977,000 | 463,000 | $ 119,000 |
Recurring |  |  |  |
Assets: |  |  |  |
Money market fund | 13,506,000 | 62,004,000 |  |
Total | 13,506,000 | 62,004,000 |  |
Recurring | Level 2 |  |  |  |
Liabilities: |  |  |  |
Total | 108,000 |  |  |
Recurring | Level 2 | Warrant Liability |  |  |  |
Liabilities: |  |  |  |
Liability | 108,000 |  |  |
Recurring | Level 3 |  |  |  |
Assets: |  |  |  |
Money market fund | 13,506,000 | 62,004,000 |  |
Total | 13,506,000 | $ 62,004,000 |  |
Liabilities: |  |  |  |
Total | 108,000 |  |  |
Recurring | Level 3 | Warrant Liability |  |  |  |
Liabilities: |  |  |  |
Liability | $ 108,000 |  |  |

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- Definition Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 14.F) -URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 14 -Section F + Details
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