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Quarterly Financial Information (Unaudited) (Details) - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 12 Months Ended
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Dec. 31, 2015 | Sep. 30, 2015 | Jun. 30, 2015 | Mar. 31, 2015 | Dec. 31, 2014 | Sep. 30, 2014 | Jun. 30, 2014 | Mar. 31, 2014 | Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Selected Quarterly Financial Information [Abstract] |  |  |  |  |  |  |  |  |  |  |
Operating expenses | $ 9,333 | $ 8,201 | $ 7,765 | $ 6,360 | $ 5,878 | $ 5,970 | $ 5,364 | $ 4,469 | $ 31,659 | $ 21,681 | $ 18,119
Net loss | $ (9,606) | $ (8,485) | $ (8,039) | $ (6,500) | $ (6,027) | $ (6,025) | $ (5,363) | $ (4,469) | $ (31,659) | $ (21,681) | $ (18,119)
Basic and Diluted (in dollars per share) | $ (0.63) | $ (0.55) | $ (8.07) | $ (13.14) | $ (14.20) | $ (13.55) | $ (13.42) | $ (11.29) | $ (4.06) | $ (51.56) | $ (47.80)
Basic and Diluted (in shares) | 15,298,810 | 15,297,794 | 996,592 | 494,590 | 424,477 | 444,787 | 399,766 | 395,774 | 8,041,948 | 424,477 | 379,025

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- Definition The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period. + References No definition available. + Details
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- Definition Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense. + References No definition available. + Details
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- Definition Average number of shares or units issued and outstanding that are used in calculating basic and diluted earnings per share (EPS). + References No definition available. + Details
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