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v3.3.1.900

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Operating activities |  |  |
Net loss | $ (32,630) | $ (21,884) | $ (18,118)
Reconciliation of net loss to net cash used in operating activities: |  |  |
Depreciation and amortization | 202 | 248 | 320
Stock-based compensation expense | 1,658 | 897 | 343
Noncash interest expense | 293 | 74 |
Changes in operating assets and liabilities: |  |  |
Prepaid expenses and other current assets | (450) | (208) | 75
Other assets | 2 |  |
Accounts payable | 196 | 481 | (129)
Accrued expenses | 954 | 8 | 1,156
Deferred rent | (18) | (28) | (13)
Net cash used in operating activities | (29,793) | (20,412) | (16,366)
Investing activities |  |  |
Purchases of available-for-sale securities |  | (4,976) |
Sales of available-for-sale-securities |  | 4,976 |
Purchases of property and equipment | (421) | (228) | (43)
Net cash used in investing activities | (421) | (228) | (43)
Financing activities |  |  |
Proceeds from initial public offering, net of issuance costs | 61,744 |  |
Proceeds from issuance of preferred stock, net of issuance costs | 12,331 |  | 41,422
Proceeds from exercise of common stock options | 91 | 118 | 27
Proceeds from borrowings | 5,000 | 5,000 |
Payments on borrowing | (833) |  |
Debt issuance costs | (7) | (284) |
Net cash provided by financing activities | 78,326 | 4,834 | 41,449
Net increase (decrease) in cash and cash equivalents | 48,112 | (15,806) | 25,040
Cash and cash equivalents, beginning of period | 14,668 | 30,474 | 5,434
Cash and cash equivalents, end of period | 62,780 | 14,668 | $ 30,474
Supplemental disclosure of cash flow information |  |  |
Cash paid for interest | 684 | 100 |
Non-cash financing activities |  |  |
Warrants for the purchase of series B preferred stock issued in conjunction with credit facility | 107 | 110 |
Initial public offering costs in accounts payable and accrued liabilities | (492) | $ 492 |
Conversion of preferred stock into common stock | 92,477 |  |
Reclassification of deferred IPO costs from non-current assets to additional paid-in capital | 1,787 |  |
Reclassification of warrant liability to additional paid-in capital | $ 206 |  |

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- Definition The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3602-108585 + Details
Name: | us-gaap_ShareBasedCompensation
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- References No definition available. + Details
Name: | us-gaap_SupplementalCashFlowInformationAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration