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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - shares
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Antidilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 2,233,114 10,477,174
Convertible preferred stock    
Antidilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares)   9,029,551
Options to purchase Common stock    
Antidilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 2,197,030 1,388,218
Warrants for purchase of Common Stock    
Antidilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 36,084 34,839
Preferred stock warrants    
Antidilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares)   24,566