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Condensed Consolidated Statements of Operations - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Operating expenses:    
Research and development $ 6,436 $ 4,616
General and administrative 2,770 1,744
Total operating expenses 9,206 6,360
Loss from operations (9,206) (6,360)
Other (expense) income:    
Interest expense (243) (149)
Interest and investment income 53  
Other (expense) income, net (22) 9
Total other expense (212) (140)
Net loss $ (9,418) $ (6,500)
Net loss per share - basic and diluted (in dollars per share) $ (0.61) $ (13.14)
Weighted-average common shares outstanding used in net loss per share - basic and diluted (in shares) 15,335,516 494,590