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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - shares
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Antidilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 2,928,063 2,233,114
Stock options    
Antidilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 2,903,497 2,197,030
Common stock warrants    
Antidilutive Common Stock Equivalents Excluded from Computation of Diluted Net Loss Per Share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 24,566 36,084