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Organization and Operations - Liquidity (Details)
$ / shares in Units, $ in Thousands
 1 Months Ended 6 Months Ended
Aug. 31, 2016
USD ($)
Jun. 30, 2017
USD ($)
$ / shares
shares
Dec. 31, 2016
USD ($)
Common stock offering      
Accumulated deficit   $ (158,920) $ (144,070)
Common Stock | Cowen      
Common stock offering      
Percentage of commission payable to underwriter based on proceeds from common stock 0.03    
Common Stock | ATM      
Common stock offering      
Number of shares issued | shares   3,641,284  
Share price (in dollars per share) | $ / shares   $ 1.80  
Additional common stock issued   $ 6,500  
Net proceeds   6,300  
Remaining common stock available for sale under offering program   $ 600  
Common Stock | ATM | Cowen      
Common stock offering      
Aggregate maximum offering amount $ 10,000