    <SEC-DOCUMENT>0001104659-17-060741-index.html : 20171004
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    <ACCEPTANCE-DATETIME>20171004083038
    ACCESSION NUMBER:		0001104659-17-060741
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		33
    CONFORMED PERIOD OF REPORT:	20171004
    ITEM INFORMATION:		Other Events
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20171004
    DATE AS OF CHANGE:		20171004

    FILER:

    	COMPANY DATA:
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    		CENTRAL INDEX KEY:			0001454789
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

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    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-37467
    		FILM NUMBER:		171120395

    	BUSINESS ADDRESS:
    		STREET 1:		ONE KENDALL SQUARE
    		STREET 2:		BLDG. 1400E, SUITE B14202
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02139
    		BUSINESS PHONE:		617-349-1971

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    		STREET 2:		BLDG. 1400E, SUITE B14202
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02139
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    Document 1 - file: a17-22790_18k.htm

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    Document 2 - file: a17-22790_1ex99d1.htm

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    Document 3 - file: a17-22790_1ex99d2.htm

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    Document 4 - file: g227901moi001.gif

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    Document 5 - file: g227901moi002.gif

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    Document 6 - file: g227901moi003.gif

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    Document 7 - file: g227901moi004.gif

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    Document 8 - file: g227901moi005.gif

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    Document 9 - file: g227901moi006.gif

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    Document 10 - file: g227901moi007.gif

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    Document 11 - file: g227901moi008.gif

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    Document 12 - file: g227901moi009.gif

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    Document 13 - file: g227901moi010.gif

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    Document 14 - file: g227901moi011.gif

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    Document 15 - file: g227901moi012.gif

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    Document 16 - file: g227901moi013.gif

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    Document 17 - file: g227901moi014.gif

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    Document 18 - file: g227901moi015.gif

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    Document 19 - file: g227901moi016.gif

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    Document 20 - file: g227901moi017.gif

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    Document 21 - file: g227901moi018.gif

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    Document 22 - file: g227901moi019.gif

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    Document 23 - file: g227901moi020.gif

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    Document 24 - file: g227901moi021.gif

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    Document 25 - file: g227901moi022.gif

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    Document 26 - file: g227901moi023.gif

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    Document 27 - file: g227901moi024.gif

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    Document 28 - file: g227901moi025.gif

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    Document 29 - file: g227901moi026.gif

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    <SEQUENCE>30
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    <TEXT>
    Document 30 - file: g227901moi027.gif

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    <SEQUENCE>31
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    Document 31 - file: g227901moi028.gif

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    <SEQUENCE>32
    <FILENAME>g227901mmi001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 32 - file: g227901mmi001.jpg

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    <SEQUENCE>33
    <FILENAME>g227901mmi002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 33 - file: g227901mmi002.jpg

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