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Stock Incentive Plans (Tables)

12 Months Ended

Dec. 31, 2017

Stock Incentive Plans

Summary of stock option activity

Shares

Weighted- Average Exercise Price

Weighted Average Remaining Contractual Term (years)

Aggregate Intrinsic Value (in thousands)

Outstanding at December 31, 2016

2,270,169

$

6.11

8.14

$

613

Granted

890,740

$

1.26

Exercised

(22,879

)

$

1.01

Cancelled or forfeited

(292,404

)

$

7.13

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Outstanding at December 31, 2017

2,845,626

$

4.53

7.75

$

216

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Vested and Exercisable at December 31, 2017

1,265,411

$

5.91

6.53

$

—

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Schedule of assumptions made based on the Black-Scholes option pricing model

		Year Ended December 31,
		2017			2016			2015
Weighted-average expected volatility			76.1 - 81.9	%		72.0 - 73.9	%		73.6 - 86.8	%
Expected term (in years)			6.25 - 9.77			6.25			6.17 - 10.00
Risk-free interest rate			2.00 - 2.38	%		1.24 - 2.00	%		0.92 - 2.45	%
Expected dividend yield			0	%		0	%		0	%

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- Definition

Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (d)
-URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
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-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (f)(2)
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