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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - shares
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Antidilutive common stock equivalents excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 3,800,192 2,928,063
Stock options    
Antidilutive common stock equivalents excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 3,775,626 2,903,497
Common stock warrants    
Antidilutive common stock equivalents excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 24,566 24,566