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Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Operating expenses:
Research and development	$ 5,247	$ 5,398
General and administrative	2,392	2,363
Total operating expenses	7,639	7,761
Loss from operations	(7,639)	(7,761)
Other (expense) income:
Interest expense	(57)	(149)
Interest and investment income	32	39
Other income (expense), net	12	(5)
Total other expense, net	(13)	(115)
Net loss	$ (7,652)	$ (7,876)
Net loss per share - basic and diluted (in dollars per share)	$ (0.29)	$ (0.41)
Weighted-average common shares outstanding used in net loss per share - basic and diluted (in shares)	26,555,840	19,093,273

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The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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