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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - shares
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Antidilutive common stock equivalents excluded from computation of diluted net loss per share        
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 45,713,786 2,826,416 45,713,786 2,826,416
Stock options        
Antidilutive common stock equivalents excluded from computation of diluted net loss per share        
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 3,689,220 2,801,850 3,689,220 2,801,850
Common stock warrants        
Antidilutive common stock equivalents excluded from computation of diluted net loss per share        
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 42,024,566 24,566 42,024,566 24,566