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Common Stock Reserved for Future Issuance (Details) - shares	Jun. 30, 2019	Dec. 31, 2018
Stockholders' equity
Shares reserved for future issuance (in shares)	7,617,536	5,589,766
Common stock warrants
Stockholders' equity
Shares reserved for future issuance (in shares)	6,193,749	4,202,449
Common stock options outstanding
Stockholders' equity
Shares reserved for future issuance (in shares)	763,592	433,389
Common stock options available for future issuance
Stockholders' equity
Shares reserved for future issuance (in shares)	547,714	877,917
Employee stock purchase plan reserved
Stockholders' equity
Shares reserved for future issuance (in shares)	112,481	76,011

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Aggregate number of common shares reserved for future issuance.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.29)
-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

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