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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Common stock
Additional paid-in capital
Accumulated deficit
Accumulated other comprehensive loss
Total
Balance at Dec. 31, 2017 $ 2 $ 183,224 $ (171,434)    
Balance (in shares) at Dec. 31, 2017 2,364,526        
Increase (Decrease) in Shareholders' Equity          
Issuance of common stock for at-the-market offerings $ 1 8,312      
Issuance of common stock for at-the-market offerings (in shares) 539,026        
Issuance of common stock and warrants in public offerings $ 4 38,907      
Issuance of common stock and warrants in public offerings (in shares) 4,200,000        
Issuance of common stock upon exercise of common stock options and warrants   4      
Issuance of common stock upon exercise of common stock options and warrants (in shares) 291        
Stock-based compensation expense   924      
Net loss     (14,131)   $ (14,131)
Balance at Jun. 30, 2018 $ 7 231,371 (185,565)   45,813
Balance (in shares) at Jun. 30, 2018 7,103,843        
Balance at Mar. 31, 2018 $ 3 192,014 (179,086)    
Balance (in shares) at Mar. 31, 2018 2,903,552        
Increase (Decrease) in Shareholders' Equity          
Issuance of common stock and warrants in public offerings $ 4 38,907      
Issuance of common stock and warrants in public offerings (in shares) 4,200,000        
Issuance of common stock upon exercise of common stock options and warrants   4      
Issuance of common stock upon exercise of common stock options and warrants (in shares) 291        
Stock-based compensation expense   446      
Net loss     (6,479)   (6,479)
Balance at Jun. 30, 2018 $ 7 231,371 (185,565)   45,813
Balance (in shares) at Jun. 30, 2018 7,103,843        
Balance at Dec. 31, 2018 $ 7 232,243 (197,304) $ (4) $ 34,942
Balance (in shares) at Dec. 31, 2018 7,141,996       7,141,996
Increase (Decrease) in Shareholders' Equity          
Issuance of common stock for at-the-market offerings $ 1 2,173      
Issuance of common stock for at-the-market offerings (in shares) 403,241        
Issuance of common stock and warrants in public offerings $ 4 18,501      
Issuance of common stock and warrants in public offerings (in shares) 4,000,000        
Issuance of common stock upon exercise of common stock options and warrants   55      
Issuance of common stock upon exercise of common stock options and warrants (in shares) 8,700        
Stock-based compensation expense   849      
Realized gain on short-term investments       5  
Net loss     (13,169)   $ (13,169)
Balance at Jun. 30, 2019 $ 12 253,821 (210,473) 1 $ 43,361
Balance (in shares) at Jun. 30, 2019 11,553,937       11,553,937
Balance at Mar. 31, 2019 $ 11 253,200 (203,342)    
Balance (in shares) at Mar. 31, 2019 11,496,242        
Increase (Decrease) in Shareholders' Equity          
Issuance of common stock for at-the-market offerings $ 1 128      
Issuance of common stock for at-the-market offerings (in shares) 49,495        
Issuance of common stock upon exercise of common stock options and warrants   52      
Issuance of common stock upon exercise of common stock options and warrants (in shares) 8,200        
Stock-based compensation expense   441      
Realized gain on short-term investments       1  
Net loss     (7,131)   $ (7,131)
Balance at Jun. 30, 2019 $ 12 $ 253,821 $ (210,473) $ 1 $ 43,361
Balance (in shares) at Jun. 30, 2019 11,553,937       11,553,937