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Summary of Significant Accounting Policies - Stock-Based Compensation (Details) - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Stock Incentive Plans    
Stock-based compensation expense $ 1,512,000 $ 1,771,000
Tax benefits recognized from stock-based compensation expense 0 0
Research and development    
Stock Incentive Plans    
Stock-based compensation expense 616,000 673,000
General and administrative    
Stock Incentive Plans    
Stock-based compensation expense $ 896,000 $ 1,098,000