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Income Taxes - Deferred tax assets (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Deferred tax assets
Net operating loss carryforwards	$ 55,283	$ 48,107
Tax credit carryforwards	8,030	7,174
Capitalized research and development	922	1,394
Capitalized legal expenses	1,073	1,132
Lease liability	639
Other differences	1,453	1,370
Total deferred tax assets	67,400	59,177
Deferred tax liabilities
ROU asset	(639)
Valuation allowance	(66,761)	(59,177)
Increase in valuation allowance	$ 7,600	$ (7,800)
Federal income tax (benefit) at statutory rate	21.00%	21.00%

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