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v3.22.0.1

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2021 | Dec. 31, 2020
Operating activities |  |
Net loss | $ (194,912) | $ (37,300)
Reconciliation of net loss to net cash used in operating activities: |  |
Non-cash portion of acquired in-process research and development | 164,612 |
Stock-based compensation expense | 3,362 | 1,390
Net gain on warrants inherited in acquisiton of Quellis | 71 |
Other non-cash items | 21 | 58
Changes in assets and liabilities: |  |
Prepaid expenses and other assets | 85 | 1,257
Right-of-use asset-operating | (109) | 176
Accounts payable | (1,965) | 347
Accrued expenses | (1,316) | 1,587
Net cash used in operating activities | (30,151) | (32,485)
Investing activities |  |
Purchases of short-term investments | (78,000) | (62,777)
Sales and maturities of short-term investments | 59,000 | 69,110
Cash acquired in acquisition of Quellis | 6,466 |
Purchases of property and equipment | (21) | (33)
Net cash provided by investing activities | (12,555) | 6,300
Financing activities |  |
Proceeds from underwritten public offering, net of issuance costs |  | 24,559
Proceeds from private offering of public equity, net of issuance costs | 104,261 |
Proceeds from at-the-market offering, net of issuance costs |  | 16,270
Proceeds from exercise of common stock options | 23 | 31
Net cash provided by financing activities | 104,284 | 40,860
Net increase in cash, cash equivalents and restricted cash | 61,578 | 14,675
Cash, cash equivalents and restricted cash, beginning of period | 25,051 | 10,376
Cash, cash equivalents and restricted cash, end of period | 86,629 | $ 25,051
Supplemental disclosure of non-cash transactions: |  |
Conversion of Series X Preferred Stock into common stock | 168,920 |
Non-cash dividend on convertible preferred stock | 24,437 |
Reclassification of warrant liability to additional paid-in capital | $ 3,468 |

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