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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Antidilutive common stock equivalents excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 8,119,614 1,260,236
Stock options    
Antidilutive common stock equivalents excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 1,346,733 227,945
Common stock warrants    
Antidilutive common stock equivalents excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 1,530,380 1,032,292
Series X Preferred Stock (1)    
Antidilutive common stock equivalents excluded from computation of diluted net loss per share    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 5,242,501