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v3.22.1

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2022 | Mar. 31, 2021
Operating activities |  |
Net loss | $ (15,323) | $ (170,084)
Reconciliation of net loss to net cash used in operating activities: |  |
Non-cash portion of acquired in-process research and development |  | 164,612
Stock-based compensation expense | 1,209 | 366
Expense for warrants inherited in acquisition of Quellis | 1,542 | 55
Other non-cash items | (79) | 4
Changes in assets and liabilities: |  |
Prepaid expenses and other assets | 163 | 767
Right-of-use asset-operating | (15) | (73)
Accounts payable | (627) | (1,712)
Accrued expenses | 571 | (2,651)
Net cash used in operating activities | (12,559) | (8,716)
Investing activities |  |
Purchases of short-term investments | (81,702) |
Sales and maturities of short-term investments | 54,603 | 20,000
Cash acquired in acquisition of Quellis |  | 6,466
Purchases of property and equipment |  | (21)
Net cash (used in) provided by investing activities | (27,099) | 26,445
Financing activities |  |
Net cash provided by financing activities |  | 104,261
Net (decrease) increase in cash, cash equivalents and restricted cash | (39,658) | 121,990
Cash, cash equivalents and restricted cash, beginning of period | 86,629 | 25,051
Cash, cash equivalents and restricted cash, end of period | $ 46,971 | $ 147,041

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