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Condensed Consolidated Statements of Redeemable Convertible Preferred Stock and Stockholders' Equity - USD ($)
$ in Thousands
Preferred stock
Series X redeemable convertible preferred stock
Common stock
Additional paid-in capital
Accumulated deficit
Accumulated other comprehensive loss
Total
Beginning balance at Dec. 31, 2020 $ 0 $ 4 $ 301,562 $ (260,897) $ 0 $ 40,669
Beginning balance (in shares) at Dec. 31, 2020 0 3,347,386        
Increase (Decrease) in Shareholders' Equity            
Issuance of preferred stock in a private offering of public equity, net of issuance costs     19,565     19,565
Issuance of preferred stock and common stock upon acquisition of Quellis     8,098     8,098
Issuance of preferred stock and common stock upon acquisition of Quellis (in shares)   555,444        
Expense related to warrants inherited in acquisition of Quellis     241     241
Stock-based compensation expense     366     366
Net loss       (170,084)   (170,084)
Ending balance at Mar. 31, 2021   $ 4 329,832 (430,981)   (101,145)
Ending balance (in shares) at Mar. 31, 2021   3,902,830        
Beginning balance at Dec. 31, 2020 $ 0 $ 4 301,562 (260,897) 0 40,669
Beginning balance (in shares) at Dec. 31, 2020 0 3,347,386        
Increase (Decrease) in Shareholders' Equity            
Net loss           (185,421)
Ending balance at Sep. 30, 2021 $ 96,398 $ 13 480,336 (446,318)   130,429
Ending balance (in shares) at Sep. 30, 2021 31,455 13,009,477        
Beginning balance at Mar. 31, 2021   $ 4 329,832 (430,981)   (101,145)
Beginning balance (in shares) at Mar. 31, 2021   3,902,830        
Increase (Decrease) in Shareholders' Equity            
Reclassification of preferred stock to permanent equity $ 240,881         240,881
Reclassification of preferred stock to permanent equity (in shares) 86,077          
Issuance of common stock upon the conversion of preferred stock $ (165,548) $ 9 165,540     1
Issuance of common stock upon the conversion of preferred stock (in shares) (53,532) 8,921,966        
Expense related to warrants inherited in acquisition of Quellis     146     146
Accretion of preferred stock discount $ 24,437   (24,437)      
Reclassification of equity classified warrants     3,468     3,468
Stock-based compensation expense     1,014     1,014
Net loss       (7,466)   (7,466)
Ending balance at Jun. 30, 2021 $ 99,770 $ 13 475,563 (438,447)   136,899
Ending balance (in shares) at Jun. 30, 2021 32,545 12,824,796        
Increase (Decrease) in Shareholders' Equity            
Issuance of common stock upon the conversion of preferred stock $ (3,372)   3,372      
Issuance of common stock upon the conversion of preferred stock (in shares) (1,090) 181,698        
Issuance of common stock upon exercise of options     6     6
Issuance of common stock upon exercise of options (in shares)   2,992        
Expense related to warrants inherited in acquisition of Quellis     385     385
Fractional shares eliminated pursuant to reverse stock split   (9)        
Stock-based compensation expense     1,010     1,010
Net loss       (7,871)   (7,871)
Ending balance at Sep. 30, 2021 $ 96,398 $ 13 480,336 (446,318)   130,429
Ending balance (in shares) at Sep. 30, 2021 31,455 13,009,477        
Beginning balance at Dec. 31, 2021 $ 96,398 $ 13 481,709 (455,809) 0 122,311
Beginning balance (in shares) at Dec. 31, 2021 31,455 13,016,955        
Increase (Decrease) in Shareholders' Equity            
Expense related to warrants inherited in acquisition of Quellis     1,542     1,542
Stock-based compensation expense     1,209     1,209
Unrealized loss on short-term investments         (53) (53)
Net loss       (15,324)   (15,324)
Ending balance at Mar. 31, 2022 $ 96,398 $ 13 484,460 (471,133) (53) 109,685
Ending balance (in shares) at Mar. 31, 2022 31,455 13,016,955        
Beginning balance at Dec. 31, 2021 $ 96,398 $ 13 481,709 (455,809) 0 122,311
Beginning balance (in shares) at Dec. 31, 2021 31,455 13,016,955        
Increase (Decrease) in Shareholders' Equity            
Issuance of common stock upon the conversion of preferred stock (in shares)   9,103,664        
Net loss           (38,571)
Ending balance at Sep. 30, 2022 $ 96,398 $ 16 511,053 (494,380) (215) 112,872
Ending balance (in shares) at Sep. 30, 2022 31,455 15,748,323        
Beginning balance at Mar. 31, 2022 $ 96,398 $ 13 484,460 (471,133) (53) 109,685
Beginning balance (in shares) at Mar. 31, 2022 31,455 13,016,955        
Increase (Decrease) in Shareholders' Equity            
Stock-based compensation expense     1,117     1,117
Unrealized loss on short-term investments         (133) (133)
Net loss       (11,250)   (11,250)
Ending balance at Jun. 30, 2022 $ 96,398 $ 13 485,577 (482,383) (186) 99,419
Ending balance (in shares) at Jun. 30, 2022 31,455 13,016,955        
Increase (Decrease) in Shareholders' Equity            
Issuance of common stock upon exercise of options     34     34
Issuance of common stock upon exercise of options (in shares)   16,202        
Stock-based compensation expense     1,155     1,155
Unrealized loss on short-term investments         (29) (29)
Issuance of common stock for at-the-market offerings, net of issuance costs   $ 3 24,287     24,290
Issuance of common stock for at-the-market offerings, net of issuance costs (in shares)   2,715,166        
Net loss       (11,997)   (11,997)
Ending balance at Sep. 30, 2022 $ 96,398 $ 16 $ 511,053 $ (494,380) $ (215) $ 112,872
Ending balance (in shares) at Sep. 30, 2022 31,455 15,748,323