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Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands | Preferred stock Series X redeemable convertible preferred stock | Common stock Underwriting agreement | Common stock at-the-market offerings | Common stock | Additional paid-in capital Underwriting agreement | Additional paid-in capital at-the-market offerings | Additional paid-in capital | Accumulated deficit | Accumulated other comprehensive loss | Underwriting agreement | at-the-market offerings | Total
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning balance at Dec. 31, 2022 | $ 96,398 |  |  | $ 28 |  |  | $ 632,512 | $ (507,643) | $ (79,000) |  |  | $ 221,216
Beginning balance (in shares) at Dec. 31, 2022 | 31,455 |  |  | 27,501,340 |  |  |  |  |  |  |  |
Increase (Decrease) in Shareholders' Equity |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock upon the conversion of preferred stock | $ (1,074) |  |  |  |  |  | 1,074 |  |  |  |  |
Issuance of common stock upon the conversion of preferred stock (in shares) | (348) |  |  | 57,910 |  |  |  |  |  |  |  |
Issuance of common stock, net of issuance costs |  | $ 8 | $ 5 |  | $ 59,472 | $ 28,493 |  |  |  | $ 59,480 | $ 28,498 |
Issuance of common stock net of issuance costs (in shares) |  | 8,253,895 | 4,738,606 |  |  |  |  |  |  |  |  |
Issuance of common stock upon exercise of options and warrants |  |  |  |  |  |  | 420 |  |  |  |  | 420
Issuance of common stock upon exercise of options and warrants (in shares) |  |  |  | 483,046 |  |  |  |  |  |  |  |
Stock-based compensation expense |  |  |  |  |  |  | 6,314 |  |  |  |  | 6,314
Unrealized gain on short-term investments |  |  |  |  |  |  |  |  | 79,000 |  |  | 79
Net Income (Loss) |  |  |  |  |  |  |  | (72,891) |  |  |  | (72,891)
Ending balance at Dec. 31, 2023 | $ 95,324 |  |  | $ 41 |  |  | 728,285 | (580,534) |  |  |  | 243,116
Ending balance (in shares) at Dec. 31, 2023 | 31,107 |  |  | 41,034,797 |  |  |  |  |  |  |  |
Increase (Decrease) in Shareholders' Equity |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock, net of issuance costs |  | $ 10 | $ 5 |  | $ 117,162 | $ 35,240 |  |  |  | $ 117,172 | $ 35,245 |
Issuance of common stock net of issuance costs (in shares) |  | 10,340,000 | 4,450,425 |  |  |  |  |  |  |  |  |
Issuance of common stock upon exercise of options and warrants |  |  |  | $ 1 |  |  | 4,784 |  |  |  |  | 4,785
Issuance of common stock upon exercise of options and warrants (in shares) |  |  |  | 608,997 |  |  |  |  |  |  |  |
Stock-based compensation expense |  |  |  |  |  |  | 13,042 |  |  |  |  | 13,042
Unrealized gain on short-term investments |  |  |  |  |  |  |  |  | 163,000 |  |  | 163
Net Income (Loss) |  |  |  |  |  |  |  | (94,260) |  |  |  | (94,260)
Ending balance at Dec. 31, 2024 | $ 95,324 |  |  | $ 57 |  |  | $ 898,513 | $ (674,794) | $ 163,000 |  |  | $ 319,263
Ending balance (in shares) at Dec. 31, 2024 | 31,107 |  |  | 56,434,219 |  |  |  |  |  |  |  |

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