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Nature of Business - Liquidity (Details) - USD ($)
$ in Thousands
 12 Months Ended
Feb. 01, 2024
Jun. 30, 2021
Dec. 31, 2024
Dec. 31, 2023
Nature of Business        
Percentage of commission paid to underwriter based on proceeds from common stock   3.00%    
Accumulated deficit     $ 674,794 $ 580,534
Cash, cash equivalents and short-term investments     $ 328,100  
Underwriting offering February 2024 Financing        
Nature of Business        
Number of shares issued 10,340,000      
Gross proceeds from issuance of common stock $ 125,000      
Net proceeds from issuance of common stock $ 117,200      
Jefferies | ATM Program        
Nature of Business        
Maximum aggregate value of common shares which can be issued under the agreement   $ 150,000    
Number of shares issued     4,450,425 4,738,606
Common stock | Underwriting offering February 2024 Financing        
Nature of Business        
Number of shares issued     10,340,000 8,253,895
Common stock | ATM Program        
Nature of Business        
Number of shares issued     4,450,425 4,738,606
Gross proceeds from issuance of common stock     $ 36,200 $ 29,400
Net proceeds from issuance of common stock     $ 35,200 $ 28,500