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Stock-Based Compensation (Tables) | 3 Months Ended
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Mar. 31, 2025
Stock-Based Compensation |
Schedule of stock option activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | Weighted | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | Average | ​ | ​ | ​
​ | ​ | ​ | ​ | Weighted- | ​ | Remaining | ​ | Aggregate
​ | ​ | ​ | ​ | Average | ​ | Contractual | ​ | Intrinsic Value
​ |  | Shares |  | Exercise Price |  | Term (years) |  | (in thousands)
Outstanding at December 31, 2024 |  | 6,850,889 | ​ | $ | 13.75 |  | 8.31 | ​ | $ | 2,946
Granted |  | 4,056,600 | ​ | $ | 6.63 | ​ | ​ | ​ | ​ | ​
Cancelled or forfeited |  | (50,182) | ​ | $ | 10.14 | ​ | ​ | ​ | ​ | ​
Expired | ​ | (289) | ​ | $ | 650.85 | ​ | ​ | ​ | ​ | ​
Outstanding at March 31, 2025 | ​ | 10,857,018 | ​ | $ | 11.09 | ​ | 8.76 | ​ | $ | 391
Vested and exercisable at March 31, 2025 | ​ | 3,057,331 | ​ | $ | 14.91 | ​ | 7.28 | ​ | $ | 281
Vested and expected to vest at March 31, 2025 |  | 10,857,018 | ​ | $ | 11.09 | ​ | 8.76 | ​ | $ | 391
Schedule of stock-based compensation expense | During the three months ended March 31, 2025 and 2024, the Company recorded stock-based compensation expense for employee and non-employee stock options and restricted stock, which was allocated as follows in the statements of operations (in thousands): ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended March 31,
​ |  | 2025 |  | 2024
General and administrative | ​ | $ | 2,537 | ​ | $ | 2,050
Research and development | ​ |  | 1,302 | ​ |  | 704
Total | ​ | $ | 3,839 | ​ | $ | 2,754

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- Definition Tabular disclosure of cost recognized for award under share-based payment arrangement by plan. Includes, but is not limited to, related tax benefit. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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