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Stock-Based Compensation (Tables)

3 Months Ended

Mar. 31, 2025

Stock-Based Compensation

Schedule of stock option activity

​

​	​	​	​	​	​	​	​	​	​	​
​	​	​	​	​		​	Weighted	​	​	​
​	​	​	​	​		​	Average	​	​	​
​	​	​	​	Weighted-		​	Remaining	​	Aggregate
​	​	​	​	Average		​	Contractual	​	Intrinsic Value
​		Shares		Exercise Price			Term (years)		(in thousands)
Outstanding at December 31, 2024		6,850,889	​	$	13.75		8.31	​	$	2,946
Granted		4,056,600	​	$	6.63	​	​	​	​	​
Cancelled or forfeited		(50,182)	​	$	10.14	​	​	​	​	​
Expired	​	(289)	​	$	650.85	​	​	​	​	​
Outstanding at March 31, 2025	​	10,857,018	​	$	11.09	​	8.76	​	$	391
Vested and exercisable at March 31, 2025	​	3,057,331	​	$	14.91	​	7.28	​	$	281
Vested and expected to vest at March 31, 2025		10,857,018	​	$	11.09	​	8.76	​	$	391

Schedule of stock-based compensation expense

During the three months ended March 31, 2025 and 2024, the Company recorded stock-based compensation expense for employee and non-employee stock options and restricted stock, which was allocated as follows in the statements of operations (in thousands):

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​	​	​	​	​	​	​
​	​	Three Months Ended March 31,
​		2025			2024
General and administrative	​	$	2,537	​	$	2,050
Research and development	​		1,302	​		704
Total	​	$	3,839	​	$	2,754

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- Definition

Tabular disclosure of cost recognized for award under share-based payment arrangement by plan. Includes, but is not limited to, related tax benefit.

+ References

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-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480429/718-10-50-2

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- Definition

Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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