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Segment Reporting (Tables) | 6 Months Ended
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Jun. 30, 2025
Segment Reporting |
Schedule of reportable segment profit and loss including significant expense categories | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended June 30, |  | Six Months Ended June 30,
​ |  | 2025 |  | 2024 |  | 2025 |  | 2024
Expenses(1): | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Research and development: | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Navenibart | ​ | $ | 11,082 | ​ | $ | 7,935 | ​ | $ | 22,911 | ​ | $ | 15,071
STAR-0310 | ​ |  | 5,738 | ​ |  | 5,710 | ​ |  | 13,174 | ​ |  | 8,685
Employee expenses | ​ |  | 4,647 | ​ |  | 3,195 | ​ |  | 9,297 | ​ |  | 6,632
General and administrative: | ​ |  | ​ | ​ |  | ​ | ​ |  | ​ | ​ |  | ​
Program support(2) | ​ |  | 373 | ​ |  | 9 | ​ |  | 344 | ​ |  | 206
Employee expenses | ​ |  | 3,330 | ​ |  | 2,736 | ​ |  | 6,854 | ​ |  | 5,598
Stock-based compensation expense | ​ |  | 4,351 | ​ |  | 3,451 | ​ |  | 8,190 | ​ |  | 6,205
Consulting and professional services expenses | ​ |  | 4,274 | ​ |  | 4,459 | ​ |  | 8,278 | ​ |  | 7,828
Other segment expenses(3) | ​ |  | 2,025 | ​ |  | 1,308 | ​ |  | 3,767 | ​ |  | 2,728
Other income, net(4) | ​ |  | (2,768) | ​ |  | (4,631) | ​ |  | (6,054) | ​ |  | (8,853)
Segment net loss | ​ | $ | 33,052 | ​ | $ | 24,172 | ​ | $ | 66,761 | ​ | $ | 44,100
(1)The significant expense categories and amounts align with segment level information that is regularly provided to the CODM. (2)General and administrative program support expense includes pre-commercial costs incurred in support of navenibart and STAR-0310, and patient advocacy costs incurred in support of navenibart and STAR-0310. (3)Other segment expenses include: costs incurred in support of overall research and development activities and non-specific programs, facilities expense, office expense, insurance expense and depreciation and amortization. (4)Other income, net, consists primarily of interest income on investments, as further described in Note 4, “Short-Term Investments”. For the three and six months ended June 30, 2025, the Company recognized interest income of $2.9 million and $6.2 million, respectively. For the three and six months ended June 30, 2024, the Company recognized interest income of $4.6 million and $8.9 million, respectively.

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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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