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Stock-Based Compensation
9 Months Ended
Sep. 30, 2025
Stock-Based Compensation  
Stock-Based Compensation

11.Stock-Based Compensation

Stock Option Activity

A summary of the Company’s stock option activity and related information follows:

Weighted

Average

Weighted-

Remaining

Aggregate

Average

Contractual

Intrinsic Value

    

Shares

    

Exercise Price

    

Term (years)

    

(in thousands)

Outstanding at December 31, 2024

 

6,850,889

$

13.75

 

8.31

$

2,946

Granted

 

4,915,310

$

6.51

Exercised

(675)

$

4.76

Cancelled or forfeited

 

(230,561)

$

9.42

Expired

(3,495)

$

805.71

Outstanding at September 30, 2025

11,531,468

$

10.51

8.36

$

5,246

Vested and exercisable at September 30, 2025

3,929,590

$

13.58

7.06

$

1,136

Vested and expected to vest at September 30, 2025

 

11,531,468

$

10.51

8.36

$

5,246

The intrinsic value of stock options exercised during the three and nine months ended September 30, 2025 was less than $0.1 million. The intrinsic value of stock options exercised during the three and nine months ended September 30, 2024 was less than $0.1 million and $0.2 million, respectively. The total grant date fair value of stock options vested for the three and nine months ended September 30, 2025 was $3.0 million and $15.2 million, respectively. The total grant date fair value of stock options vested for the three and nine months ended September 30, 2024 was $1.6 million and $7.2 million, respectively. The weighted-average grant date fair value per share of options granted for the three and nine months ended September 30, 2025 was $4.38 and $4.54, respectively. The weighted-average grant date fair value per share of options granted for the three and nine months ended September 30, 2024 was $7.32 and $9.66, respectively.

As of September 30, 2025, the total unrecognized compensation expense related to unvested stock option awards was $41.6 million. The Company expects to recognize that cost over a weighted-average period of approximately 2.7 years.

Stock-Based Compensation Expense

During the three and nine months ended September 30, 2025 and 2024, the Company recorded stock-based compensation expense for employee and non-employee stock options and restricted stock, which was allocated as follows in the statements of operations (in thousands):

Three Months Ended September 30, 

Nine Months Ended September 30, 

    

2025

    

2024

    

2025

    

2024

General and administrative

$

2,698

$

2,382

$

7,964

$

6,963

Research and development

1,610

1,052

 

4,534

 

2,676

Total

$

4,308

$

3,434

$

12,498

$

9,639

No related tax benefits were recognized during the three and nine months ended September 30, 2025 and 2024.