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Summary of Significant Accounting Policies - Additional Information (Detail)
$ / shares in Units, $ in Thousands
 1 Months Ended 3 Months Ended
Jun. 30, 2021
USD ($)
ft²
Mar. 31, 2023
USD ($)
shares
Mar. 31, 2022
USD ($)
Dec. 31, 2022
USD ($)
shares
Dec. 31, 2021
USD ($)
Nov. 30, 2020
$ / shares
shares
Significant Accounting Policies [Line Items]            
Restricted cash deposit   $ 1,833   $ 1,833    
Restricted cash noncurrent   1,833 $ 2,070 $ 1,833 $ 2,070  
Proceeds from financing liabilities   $ 2,143        
Common stock, shares issued | shares   19,573,132   19,556,732    
Payment of exchange fees   $ 517 $ 235      
Common stock shares issued warrant to purchase | shares           2,000
Common stock warrants exercise price per share | $ / shares           $ 49.35
Office laboratory [Member] | Hood Park LLC [Member]            
Significant Accounting Policies [Line Items]            
Area of lease agreement | ft² 49,869          
Lease description   The Company relocated its corporate headquarters to the Premises in June 2022. The initial term of the lease commenced in June 2022 when the construction of the lessor assets was substantially completed and continues for a ten-year period, unless earlier terminated. The lease provides the Company with an option to extend the lease for an additional five-year term. The Company and the Landlord were each obligated to undertake certain improvements prior to the commencement of the lease, and significant improvements were completed as of June 2022.        
Operating lease, monthly payments $ 305          
Operating lease payments annual escalation percentage 3.00%          
Construction allowance $ 10,223          
Letter of credit amount   $ 1,833